For pharmaceutical manufacturers, the reliable sourcing of high-quality intermediates is paramount. One such critical compound is 3,4,5-Trimethoxybenzaldehyde, identified by CAS number 86-81-7. This chemical plays an indispensable role as a precursor in the synthesis of Trimethoprim, an essential antibiotic widely used for its synergistic antibacterial properties. Understanding the nuances of sourcing this compound, including its specifications and key suppliers, is vital for maintaining a robust production chain.

Understanding 3,4,5-Trimethoxybenzaldehyde

3,4,5-Trimethoxybenzaldehyde, often abbreviated as TMBA, is characterized by its molecular formula C10H12O4 and a molecular weight of 196.200. It typically presents as a white to yellowish needle crystal, with a specified purity of 99% minimum. Its melting point hovers between 72-74 °C, and it possesses a density of approximately 1.1 g/cm³. These specifications are crucial for formulators and researchers to ensure the efficacy and consistency of their final pharmaceutical products. For those looking to buy 3,4,5-trimethoxybenzaldehyde pharmaceutical intermediate, these details are non-negotiable.

The Role in Trimethoprim Synthesis

The primary application driving the demand for 3,4,5-Trimethoxybenzaldehyde is its function as a key building block in the multi-step synthesis of Trimethoprim. Trimethoprim is a bacteriostatic antibiotic that works by inhibiting dihydrofolate reductase, an enzyme essential for bacterial DNA synthesis. Its efficacy is often enhanced when used in combination with sulfamethoxazole, creating a potent antimicrobial synergy. Therefore, the quality of the 3,4,5-trimethoxybenzaldehyde used directly impacts the yield and purity of the final Trimethoprim active pharmaceutical ingredient (API).

Sourcing Strategies and Key Suppliers in China

When sourcing 3,4,5-Trimethoxybenzaldehyde, particularly for large-scale pharmaceutical production, identifying reliable 3,4,5-trimethoxybenzaldehyde supplier China is a strategic imperative. Manufacturers specializing in fine chemicals and pharmaceutical intermediates are best equipped to meet stringent quality control standards. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on providing high-purity intermediates, ensuring batch-to-batch consistency and reliable delivery. For procurement managers, understanding the CAS 86-81-7 price and inquiring about bulk order discounts is a standard practice to optimize costs.

“We are committed to being a premier 3,4,5-trimethoxybenzaldehyde manufacturer, offering competitive pricing and unwavering quality to our global clientele,” states a representative from NINGBO INNO PHARMCHEM CO.,LTD. “Our aim is to support the pharmaceutical industry by ensuring a steady and dependable supply of critical precursors like CAS 86-81-7, facilitating the production of life-saving medications.”

Conclusion

For any pharmaceutical company involved in the production of antibacterial agents like Trimethoprim, securing a consistent and high-quality supply of 3,4,5-Trimethoxybenzaldehyde is essential. By partnering with reputable manufacturers and suppliers in China, businesses can ensure product integrity, cost-effectiveness, and a resilient supply chain. If you are looking to purchase this vital intermediate, reaching out to established suppliers for a quote is the first step towards a successful collaboration.