In the intricate world of organic synthesis, the availability of high-quality building blocks is crucial for researchers and chemists. 2-Methyl-4(5)-iodo-1H-imidazole, identified by CAS number 73746-45-9, stands out as a valuable intermediate, offering a unique structural motif for complex molecular construction. This article delves into its applications, chemical properties, and how you can effectively purchase it from reputable manufacturers.

The Chemical Profile of 2-Methyl-4(5)-iodo-1H-imidazole:

This imidazole derivative, often appearing as an off-white to light yellow solid, possesses a molecular weight of 208.00 g/mol. Its IUPAC name variations include 4-Iodo-2-methyl-1H-imidazole and 5-Iodo-2-methyl-1H-imidazole, highlighting the tautomeric nature of the imidazole ring. The presence of the iodine atom makes it particularly amenable to various coupling reactions, such as Suzuki, Stille, or Sonogashira couplings, which are cornerstones of modern synthetic chemistry. Its utility extends across diverse research areas, from developing novel pharmaceuticals to creating advanced materials.

Applications in Synthesis:

  • Pharmaceutical Development: As a pharmaceutical intermediate, 2-Methyl-4(5)-iodo-1H-imidazole is a key component in the synthesis of active pharmaceutical ingredients (APIs). Its imidazole core is found in many biologically active molecules, and the iodo substituent allows for facile introduction of diverse functional groups, leading to new drug candidates. Researchers often seek to buy this compound for lead optimization and library synthesis.
  • Agrochemical Research: Similar to pharmaceuticals, the development of new agrochemicals often relies on complex heterocyclic structures. This intermediate can be employed in the synthesis of novel pesticides, herbicides, or fungicides.
  • Materials Science: The unique electronic properties of iodine-containing heterocycles can be leveraged in the development of new functional materials, such as organic semiconductors or components for optoelectronic devices.
  • General Organic Synthesis: Beyond specific industries, it serves as a general reagent for academic and industrial chemists looking to introduce a functionalized imidazole moiety into larger molecules. Its predictable reactivity makes it a reliable choice for challenging synthetic targets.

Sourcing Strategies for Researchers:

When embarking on a project requiring 2-Methyl-4(5)-iodo-1H-imidazole, the first step for a researcher or lab manager is to identify dependable sources. A 'chemical supplier' or 'manufacturer' specializing in organic intermediates is your best bet. Many companies, particularly those based in China, offer this compound with various purity levels and quantities. It is advisable to compare pricing and product specifications from multiple suppliers before making a purchase. For example, if you are looking for a 'price for 73746-45-9', obtaining quotes from several vendors will help you secure a cost-effective solution.

The Value Proposition of a Reliable Supplier:

Choosing a manufacturer that prioritizes quality control and consistent production is paramount. A good supplier will provide detailed Certificates of Analysis (CoA) and ensure that the product's physical and chemical properties align with the stated specifications. This not only guarantees the success of your synthesis but also saves valuable research time and resources. For those needing a '4-iodo-2-methyl-1h-imidazole supplier', focus on companies that offer readily available stock and responsive customer service.

In summary, 2-Methyl-4(5)-iodo-1H-imidazole is a versatile and indispensable tool for modern organic synthesis. By understanding its applications and adopting a strategic approach to sourcing, researchers and chemists can readily acquire this essential intermediate from reliable manufacturers, powering their innovation in chemistry and beyond.