In the competitive landscape of pharmaceutical ingredient sourcing, understanding and verifying the specifications of key intermediates like Diethyl (tosyloxy)methylphosphonate (CAS 31618-90-3) is crucial for any discerning buyer. As a vital component in the synthesis of Tenofovir and other advanced chemical processes, its quality directly impacts the success of your manufacturing or R&D efforts. Partnering with a reputable manufacturer who provides detailed, accurate specifications is essential.

The most critical specification for Diethyl (tosyloxy)methylphosphonate is its purity. Typically, pharmaceutical-grade intermediates are expected to have a purity level of 98.5% or higher, often determined by Gas Chromatography (GC). A reliable manufacturer will clearly state this purity on their product data sheets and provide a lot-specific Certificate of Analysis (CoA) upon request. This CoA should detail not only the overall purity but also the levels of specific impurities, such as moisture content (typically ≤0.5%) and residual solvents like toluene (≤1.0%) or ethyl p-toluenesulfonate (≤0.5%).

Appearance is another key identifier. Diethyl (tosyloxy)methylphosphonate is consistently described as a clear, colorless to pale yellow oily liquid. Any significant deviation from this description could indicate contamination or degradation, making it important for buyers to visually inspect the product upon receipt and compare it against the manufacturer's description.

Physical properties such as density and refractive index are also important for confirming the identity and quality of the compound. A density around 1.255 and a refractive index in the range of 1.4980-1.5020 are commonly cited. While these might not be routinely checked by every buyer, having this data from the manufacturer assures consistency in their production batches.

For handling and storage, manufacturers usually provide guidelines. Diethyl (tosyloxy)methylphosphonate is often recommended to be stored in a cool, ventilated place, or under inert atmosphere at 2-8°C to maintain its stability. Proper storage conditions help preserve the intermediate's integrity until it is used. Buyers should also be aware of the handling precautions and hazard statements associated with the chemical, as outlined in the Material Safety Data Sheet (MSDS).

When you are ready to buy Diethyl (tosyloxy)methylphosphonate, it is vital to choose a manufacturer that not only meets these specifications but also provides comprehensive documentation and reliable customer support. By diligently reviewing the specifications provided by potential suppliers, you can ensure that you are sourcing a high-quality intermediate that will perform optimally in your applications, whether for R&D or large-scale Tenofovir production.

As a leading supplier and manufacturer, we are committed to providing Diethyl (tosyloxy)methylphosphonate that adheres to the highest industry standards. Contact us to learn more about our product specifications and to discuss your sourcing needs with our expert team.