For professionals in the pharmaceutical and fine chemical industries, the procurement of chemical intermediates is a critical process governed by stringent quality requirements. 2,4-Dichloro-5-methoxyaniline (CAS: 98446-49-2) is a prime example of such an intermediate, vital for the synthesis of pharmaceuticals like Bosutinib. Ensuring the quality of this compound is paramount, and this involves understanding its key specifications and how to effectively source it from reliable manufacturers and suppliers.

The primary specification for 2,4-Dichloro-5-methoxyaniline, when sourcing it to buy, is its purity. Typically, pharmaceutical applications demand a purity of 98.0% or higher, commonly verified through Gas Chromatography (GC). This high level of purity is essential to minimize impurities that could interfere with subsequent synthetic steps or affect the final drug product's efficacy and safety profile. Suppliers should readily provide a Certificate of Analysis (CoA) detailing the purity and the analytical methods used.

The chemical identity must be unequivocally confirmed. The CAS Number 98446-49-2 is the universal identifier, and its presence should be verified on all product documentation. Synonyms such as 5-Amino-2,4-dichloroanisole or 4,6-Dichloro-m-anisidine are also important to recognize. The molecular formula (C7H7Cl2NO) and molecular weight (approximately 192.04 g/mol) are also fundamental identifiers that should align with supplier information.

Physical characteristics are another set of important specifications. 2,4-Dichloro-5-methoxyaniline typically presents as a pale yellow solid. Its melting point, usually around 51°C, serves as a good indicator of purity. Information regarding solubility, such as its slight solubility in chloroform and methanol, can also be relevant for chemists designing synthesis routes. When seeking a 2,4-Dichloro-5-methoxyaniline manufacturer, inquiring about these physical properties and ensuring they match expectations is advisable.

Beyond the intrinsic quality of the compound itself, the reliability of the supplier is a crucial factor. For professionals seeking a Bosutinib intermediate supplier, it’s important to look for companies with a robust quality management system, consistent production capabilities, and a strong reputation in the market. Manufacturers based in China are often significant sources, offering competitive pricing for this intermediate. When comparing the CAS 98446-49-2 price, also consider the supplier’s adherence to international quality standards and their ability to provide regulatory support.

Furthermore, safe handling and storage information, typically found in the Material Safety Data Sheet (MSDS), should be readily available. This document outlines potential hazards, recommended protective measures, and appropriate storage conditions, usually suggesting a cool, dry, and dark place. Ensuring that the pharmaceutical intermediate for sale comes with comprehensive safety data is a non-negotiable aspect of procurement.

In conclusion, sourcing high-quality 2,4-Dichloro-5-methoxyaniline requires a diligent approach to verifying its specifications. By focusing on purity, identity, physical properties, and supplier reliability, procurement professionals can secure this vital intermediate, underpinning the success of their pharmaceutical manufacturing and research endeavors.