In the intricate world of pharmaceutical manufacturing, the identification and sourcing of high-quality chemical intermediates are fundamental to success. 2,4-Dichloro-5-methoxyaniline, identified by its CAS number 98446-49-2, stands out as a critical compound, primarily utilized as an intermediate in the synthesis of Bosutinib, an important oncology drug. This article aims to provide a comprehensive overview of this chemical, covering its properties, applications, and the considerations for procurement by industry professionals.

Chemically known as 5-Amino-2,4-dichloroanisole, 2,4-Dichloro-5-methoxyaniline is an aromatic amine characterized by its molecular formula C7H7Cl2NO and a molecular weight of approximately 192.04 g/mol. Its physical form is typically a pale yellow solid, with a melting point reported around 51°C. The compound exhibits moderate solubility in common organic solvents such as chloroform and methanol, which is a key factor for its use in various synthetic processes. Professionals looking to buy 2,4-Dichloro-5-methoxyaniline should always verify the purity, which is generally expected to be 98.0% or higher via GC analysis.

The primary and most significant application of 2,4-Dichloro-5-methoxyaniline lies in its role as a key building block for Bosutinib. Bosutinib is a BCR-ABL and Src family kinase inhibitor that has demonstrated efficacy in treating certain types of leukemia. The precise structure of 2,4-Dichloro-5-methoxyaniline allows for its integration into the complex molecular architecture of Bosutinib, contributing to the drug's therapeutic activity. Therefore, ensuring a consistent and high-quality supply of this intermediate is vital for pharmaceutical companies manufacturing Bosutinib.

For procurement managers and R&D scientists, understanding the global market for this intermediate is crucial. China is a major hub for chemical manufacturing, and many reliable 2,4-Dichloro-5-methoxyaniline manufacturers are located there. When seeking to procure this chemical, it is advisable to compare pricing from multiple suppliers, considering factors like minimum order quantities, lead times, and the availability of necessary regulatory documentation. The CAS 98446-49-2 price will fluctuate, making it important to stay informed about market trends.

When engaging with a Bosutinib intermediate supplier, it is important to assess their manufacturing capabilities and quality control processes. A reputable pharmaceutical intermediate for sale provider will be transparent about their production methods and quality assurance. They should also be able to provide detailed product specifications and safety data, ensuring that the intermediate meets all necessary industry standards for pharmaceutical use.

In conclusion, 2,4-Dichloro-5-methoxyaniline is an indispensable chemical intermediate for the pharmaceutical industry, especially for the synthesis of Bosutinib. By understanding its properties and critically evaluating potential suppliers, companies can secure a reliable source of this vital compound, ensuring the integrity and efficiency of their drug manufacturing processes.