In the fast-paced world of chemical research and development, access to high-quality, specialized intermediates is essential for innovation. Ethyl Trifluoromethylpropiolate, more commonly known as Ethyl 4,4,4-Trifluorobut-2-ynoate (CAS: 79424-03-6), is one such compound that has gained significant traction due to its unique structural features and reactivity. This article explores its properties and applications, guiding researchers on how to effectively source this vital building block.

Chemical Profile and Properties

Ethyl 4,4,4-Trifluorobut-2-ynoate is a colorless liquid with the molecular formula C6H5F3O2 and a molecular weight of 166.10 g/mol. Its defining characteristic is the presence of a trifluoromethyl group attached to an acetylenic ester. This combination imparts distinct electronic and steric properties, making it a sought-after reagent in synthetic organic chemistry.

Key physical properties include:

  • Purity: Typically offered at 97% or higher, with 99% purity being a common specification for demanding research applications.
  • Boiling Point: Approximately 96-98°C, facilitating its use in reactions under various temperature conditions.
  • Density: Around 1.162 g/mL at 25°C, useful for volumetric measurements and reaction calculations.

Applications in Research and Development

The primary utility of Ethyl Trifluoromethylpropiolate lies in its role as a versatile intermediate in organic synthesis. Its ability to readily participate in nucleophilic additions and cycloaddition reactions makes it invaluable for creating complex fluorinated molecules. A prominent example is its use in the synthesis of 2-fluoroalkylated 1,3-benzodioxole derivatives, often employed in the development of new pharmaceutical candidates. For R&D scientists, having a dependable source to buy Ethyl 4,4,4-Trifluorobut-2-ynoate is critical for advancing their research projects efficiently.

Sourcing Reliable Suppliers

When procuring Ethyl Trifluoromethylpropiolate for R&D purposes, it is crucial to partner with reputable suppliers who can guarantee product quality and timely delivery. As a leading manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-grade chemicals, including CAS 79424-03-6. We understand that researchers require not only competitive price but also assurance of purity and consistency for their experiments. Whether you need small quantities for initial screening or larger amounts for scale-up studies, we are equipped to meet your demands.

We invite you to explore our offerings and request a quote or sample. Let NINGBO INNO PHARMCHEM CO.,LTD. be your trusted partner in sourcing high-quality Ethyl Trifluoromethylpropiolate and other essential chemical intermediates for your groundbreaking research. Our commitment is to provide the materials you need to accelerate scientific discovery.