For procurement professionals and chemists in the pharmaceutical and fine chemical industries, sourcing critical intermediates like (S)-1-tosyl-3-(1-cyano-1,1-diphenylmethyl)pyrrolidine (CAS: 133099-09-9) requires a strategic approach. This chiral compound is a key building block for Darifenacin synthesis, and its quality directly impacts the final API. This guide aims to equip buyers with the knowledge to effectively source this essential intermediate, focusing on what to look for in a reliable manufacturer and supplier.

The market for pharmaceutical intermediates is global, with a significant number of high-quality manufacturers located in China. When you are looking to buy (S)-1-tosyl-3-(1-cyano-1,1-diphenylmethyl)pyrrolidine, it's essential to prioritize suppliers who can demonstrate:

  • High Purity and Consistent Quality: The primary specification for this intermediate is its purity, typically requiring ≥99.0%. Look for suppliers who provide detailed Certificates of Analysis (CoA) confirming chemical purity and, importantly, stereochemical purity, as the (S) configuration is critical.
  • Manufacturing Expertise: A strong understanding of chiral synthesis is vital. Partner with a manufacturer that specializes in complex organic synthesis and has a proven track record of producing intermediates like CAS 133099-09-9 consistently.
  • Reliable Supply Chain: Ensure the supplier has the capacity to meet your volume requirements, from R&D scale to commercial production. A stable and dependable supply chain is crucial to avoid production delays.
  • Competitive Pricing: While quality is paramount, cost-effectiveness is also a key consideration. Chinese manufacturers often offer competitive pricing due to efficient production processes and economies of scale.
  • Regulatory Compliance: While not always mandatory for intermediates, understanding the supplier's adherence to quality management systems (e.g., ISO) can be an indicator of their commitment to quality.

When you search for a (S)-1-tosyl-3-(1-cyano-1,1-diphenylmethyl)pyrrolidine manufacturer, consider companies that openly share product specifications, safety data sheets (MSDS), and are responsive to inquiries. For example, inquiring about the price of CAS 133099-09-9 should be part of your evaluation, but it should be balanced against the supplier's overall credibility and quality assurance processes.

As a leading pharmaceutical intermediate supplier from China, we are committed to meeting these buyer expectations. We offer high-purity (S)-1-tosyl-3-(1-cyano-1,1-diphenylmethyl)pyrrolidine with robust quality documentation and competitive pricing. Our expertise in chiral synthesis and our reliable manufacturing capabilities ensure that you receive a product that meets your stringent requirements. We encourage you to request a quote and experience the benefits of sourcing this critical intermediate from a trusted partner dedicated to advancing your pharmaceutical projects.