Exploring the Chemistry of (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-Methylpent-2-enoic Acid
NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing advanced chemical intermediates that are crucial for complex synthesis. Today, we focus on (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-Methylpent-2-enoic acid (CAS 1012341-48-8), a molecule whose intricate structure and specific properties make it invaluable in modern chemistry.
This compound is defined by its chemical formula C23H27NO4 and a molecular weight of 381.46. The presence of a biphenyl group attached to a pentenoic acid backbone, along with a protected amino group (tert-butoxycarbonyl), gives it unique reactivity and application potential. The (R,E) designation indicates specific stereochemistry at its chiral center and the configuration of the double bond, which are critical for its function as a chiral building block in stereoselective synthesis. Its typical appearance as a white to off-white solid, with a melting point of 188-191°C, further describes its physical characteristics.
The primary utility of this compound is as a key intermediate in the synthesis of sacubitril, a vital component in cardiovascular medications. The pharmaceutical industry relies on such sophisticated intermediates for the efficient and reliable production of complex drug molecules. The sacubitril intermediate production process benefits greatly from the pre-defined chirality and functional groups present in this molecule. This aspect makes it a cornerstone for companies involved in pharmaceutical intermediate production.
Chemists often seek out molecules with specific functionalities for their research. As a protected amino acid derivative, (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-Methylpent-2-enoic acid is highly valued in peptide synthesis and the construction of other complex biomolecules. Furthermore, its nature as a biphenyl derivative chemical makes it attractive for applications requiring enhanced thermal stability, specific optical properties, or unique electronic characteristics, opening doors in materials science and other advanced fields.
The synthesis of such specialized chemicals requires precision and expertise. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity materials that enable seamless organic synthesis. Our dedication to quality ensures that researchers and manufacturers can depend on the integrity of our products, whether for small-scale laboratory experiments or large-scale industrial production. We aim to be your trusted partner in advancing chemical innovation by supplying the fundamental building blocks for your most demanding projects.
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