The strategic incorporation of fluorine atoms into organic molecules has become a cornerstone of modern chemical innovation, particularly in pharmaceuticals, agrochemicals, and materials science. Fluorinated building blocks offer unique physicochemical properties that can dramatically improve the performance and efficacy of the final products. Among these, 3,4,5-Trifluorophenylboronic acid is a highly valued reagent. For procurement professionals and research scientists aiming to leverage these advantages, understanding its attributes and sourcing options is vital.

The Impact of Fluorine Substitution
Fluorine's high electronegativity and small atomic radius contribute to several key effects when incorporated into organic structures. These include increased lipophilicity, enhanced metabolic stability (by blocking metabolic oxidation sites), altered pKa values, and unique electronic interactions. In the case of 3,4,5-Trifluorophenylboronic acid (CAS: 143418-49-9), the three fluorine atoms on the phenyl ring create a significantly electron-deficient aromatic system. This electronic nature influences its reactivity in synthetic transformations and the properties of molecules derived from it.

Properties and Availability of 3,4,5-Trifluorophenylboronic Acid
Typically supplied as a white to off-white crystalline solid, 3,4,5-Trifluorophenylboronic acid is characterized by its chemical formula C6H4BF3O2 and a molecular weight of 175.90 g/mol. We ensure our product maintains a high purity, with an assay of ≥98.0%, which is critical for reproducible results in sensitive synthetic procedures. Our manufacturing capabilities in China allow us to provide this essential building block efficiently and at competitive prices. If you are looking to buy this compound, consider the benefits of sourcing from a direct manufacturer.

Key Application Areas
1. Drug Discovery and Medicinal Chemistry: The trifluorophenyl moiety is frequently incorporated into drug candidates to improve their pharmacological profiles. It can enhance binding affinity to target proteins, increase cell membrane permeability, and prolong in vivo half-life. Pharmaceutical companies regularly seek to buy such fluorinated intermediates for their lead optimization programs.

2. Advanced Materials Development: In materials science, fluorinated aromatics are integral to creating materials with specific thermal, optical, or electronic properties. This includes high-performance polymers, liquid crystals, and organic semiconductors. The electron-withdrawing nature of the trifluorophenyl group can tune the electronic band gap and dielectric constants of materials.

3. Organic Synthesis Reagent: Beyond specific industry applications, 3,4,5-Trifluorophenylboronic acid serves as a versatile reagent in academic and industrial research laboratories for constructing complex organic frameworks. Its predictable reactivity in reactions like Suzuki coupling makes it a reliable tool for chemists. We are a trusted supplier for such research chemicals.

Why Partner with Us for Your Chemical Needs?
As a prominent manufacturer and supplier, we are committed to delivering high-quality 3,4,5-Trifluorophenylboronic acid to the global market. Our focus on stringent quality control and efficient production ensures you receive a product that meets your exacting standards. By choosing us, you benefit from competitive pricing, reliable supply, and dedicated customer support. If your organization requires a dependable source for this crucial fluorinated building block, we are here to serve your purchasing needs. Contact us to learn more or to request a quote for bulk orders.