Fmoc-Asp-OAll: Key Intermediate for Custom Peptide Synthesis
In the dynamic field of custom peptide synthesis, the selection of high-quality building blocks is paramount. Fmoc-Asp-OAll, scientifically recognized as N-alpha-Fmoc-L-Aspartic Acid Alpha-Allyl Ester and bearing the CAS number 144120-53-6, is a highly sought-after intermediate. Its specific chemical structure and orthogonal protection strategy make it an essential component for creating peptides with precise modifications. As a dedicated manufacturer and supplier, we provide this crucial reagent to meet the exacting demands of the peptide synthesis industry.
The primary utility of Fmoc-Asp-OAll lies in its application within the Fmoc solid-phase peptide synthesis (SPPS) methodology. The N-terminal Fmoc group is base-labile, allowing for facile removal during peptide chain elongation. Concurrently, the allyl ester protecting the beta-carboxyl side chain of aspartic acid offers an orthogonal deprotection pathway. This allyl ester can be selectively cleaved using palladium-based reagents, a process that is milder and more selective than acid-based cleavage methods, thereby preserving other acid-sensitive protecting groups. This feature is particularly important for synthesizing peptides with complex structures or for those requiring specific side-chain manipulations. Typically supplied as a white powder, Fmoc-Asp-OAll requires storage at 2-8°C to maintain its stability and reactivity.
For researchers and procurement specialists needing to buy Fmoc-Asp-OAll, choosing a reliable manufacturer is key to ensuring product quality and consistency. Purity levels, often verified through HPLC analysis, are typically expected to be 98% or higher to guarantee successful and reproducible synthesis outcomes. Chinese manufacturers have established themselves as significant global suppliers of fine chemicals and pharmaceutical intermediates, offering a compelling combination of advanced manufacturing capabilities and competitive pricing. We are proud to be among these leading suppliers, committed to delivering exceptional quality for your custom peptide synthesis projects.
The development of new peptide-based therapeutics and diagnostic agents is a rapidly growing area. Consequently, the demand for specialized amino acid derivatives like Fmoc-Asp-OAll continues to rise. Whether your requirements are for grams for initial research or kilograms for scaled-up production, our robust manufacturing infrastructure ensures a dependable supply. We encourage potential buyers to inquire about our product specifications, pricing, and availability. By partnering with us, you gain access to a reliable source for this critical peptide synthesis reagent.
In summary, Fmoc-Asp-OAll (CAS 144120-53-6) is a vital intermediate for custom peptide synthesis, offering distinct advantages through its orthogonal protection system. We invite you to explore our capabilities as a premier Chinese manufacturer and supplier and to buy Fmoc-Asp-OAll to enhance the precision and efficiency of your peptide synthesis workflows.
Perspectives & Insights
Alpha Spark Labs
“The development of new peptide-based therapeutics and diagnostic agents is a rapidly growing area.”
Future Pioneer 88
“Consequently, the demand for specialized amino acid derivatives like Fmoc-Asp-OAll continues to rise.”
Core Explorer Pro
“Whether your requirements are for grams for initial research or kilograms for scaled-up production, our robust manufacturing infrastructure ensures a dependable supply.”