The field of custom peptide synthesis has seen remarkable growth, fueled by its applications in drug discovery, diagnostics, and therapeutics. At the heart of this complex process lies a repertoire of highly specialized reagents, among which Fmoc-Cys(Trt)-OH holds significant importance. For anyone involved in ordering or supplying custom peptides, understanding this building block is key.

The Role of Fmoc-Cys(Trt)-OH in Custom Synthesis

Custom peptide synthesis involves assembling a specific sequence of amino acids, often with modifications. Cysteine, due to its sulfur-containing side chain, requires careful protection to prevent unwanted reactions during the assembly process. Fmoc-Cys(Trt)-OH serves this exact purpose. The Fmoc group on the alpha-amino terminus is standard for solid-phase peptide synthesis (SPPS), allowing for controlled chain elongation. The trityl (Trt) group attached to the sulfur atom of cysteine provides robust protection for the thiol side chain, which is stable under typical SPPS conditions but can be readily removed at the end of the synthesis.

Specifications and Quality Assurance

When you buy Fmoc-Cys(Trt)-OH for custom synthesis projects, you need assurance of quality and consistency. Key specifications to look for include:

  • Purity: High purity, typically ≥99.0% by HPLC, is essential to ensure clean coupling reactions and high yields of the target peptide.
  • Enantiomeric Purity: For L-cysteine derivatives, high enantiomeric purity is critical for producing biologically active peptides.
  • Stability: Proper storage and handling ensure the reagent maintains its integrity.

The CAS number for this compound is 103213-32-7, and its molecular formula is C37H31NO4S. As a manufacturer, we ensure that each batch meets these stringent quality controls, making us a reliable source for custom peptide synthesis providers.

Supplier Considerations for Custom Peptide Needs

For companies that offer custom peptide synthesis services, reliable access to high-quality building blocks like Fmoc-Cys(Trt)-OH is non-negotiable. Partnering with a manufacturer that understands these demands means:

  • Consistent Supply: Ensuring you can meet the demand from your clients.
  • Competitive Pricing: Helping you maintain profitability in a competitive market.
  • Technical Support: Access to expertise for troubleshooting or understanding product applications.

We are a leading manufacturer and supplier of these crucial reagents, committed to supporting the custom peptide synthesis industry. By choosing us, you are selecting a partner dedicated to providing the essential, high-purity building blocks that form the foundation of successful custom peptide projects.