Fmoc-HomoArg(Pbf)-OH: Your High-Purity Building Block for Peptide Drug Discovery
In the intricate world of drug discovery, particularly in the realm of peptide-based therapeutics, the quality of the chemical building blocks used is paramount. Fmoc-HomoArg(Pbf)-OH, a sophisticated derivative of homoarginine, has emerged as an indispensable tool for researchers pushing the boundaries of pharmaceutical innovation. As a key pharmaceutical intermediate, its role in complex peptide synthesis is vital for developing new treatments.
Fmoc-HomoArg(Pbf)-OH, bearing the CAS number 401915-53-5, is characterized by its high purity, typically exceeding 98%. This level of purity is critical for ensuring the accuracy and reproducibility of peptide synthesis, especially when employing the Fmoc (9H-fluoren-9-ylmethoxycarbonyl) solid-phase peptide synthesis (SPPS) strategy. The compound's structure is designed to facilitate the efficient coupling of homoarginine residues while protecting reactive functional groups, thereby preventing undesired side reactions and structural defects in the final peptide product.
The Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group integrated into Fmoc-HomoArg(Pbf)-OH provides robust protection for the guanidino moiety of homoarginine. This protection is essential for maintaining the integrity of the amino acid during the iterative cycles of deprotection and coupling inherent in SPPS. As a result, this Pbf protected homoarginine derivative is a preferred choice for synthesizing peptides with sensitive sequences or complex architectures.
For companies involved in custom peptide synthesis, sourcing high-quality Fmoc-HomoArg(Pbf)-OH is a strategic imperative. Its application as a custom peptide synthesis chemical enables the creation of tailored peptide sequences designed to interact with specific biological targets. This capability accelerates the identification and optimization of lead compounds in drug discovery programs. By partnering with reliable manufacturers and suppliers of this essential amino acid derivative, research institutions and pharmaceutical companies can ensure the success of their demanding projects.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing a consistent supply of this high-purity peptide synthesis building block. Our commitment ensures that researchers have access to the quality materials needed to drive innovation in peptide drug discovery, contributing to the development of next-generation therapies. Proper handling and storage, including maintaining a cool environment at 0°C, are crucial for preserving the compound's optimal performance and purity.
Fmoc-HomoArg(Pbf)-OH, bearing the CAS number 401915-53-5, is characterized by its high purity, typically exceeding 98%. This level of purity is critical for ensuring the accuracy and reproducibility of peptide synthesis, especially when employing the Fmoc (9H-fluoren-9-ylmethoxycarbonyl) solid-phase peptide synthesis (SPPS) strategy. The compound's structure is designed to facilitate the efficient coupling of homoarginine residues while protecting reactive functional groups, thereby preventing undesired side reactions and structural defects in the final peptide product.
The Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group integrated into Fmoc-HomoArg(Pbf)-OH provides robust protection for the guanidino moiety of homoarginine. This protection is essential for maintaining the integrity of the amino acid during the iterative cycles of deprotection and coupling inherent in SPPS. As a result, this Pbf protected homoarginine derivative is a preferred choice for synthesizing peptides with sensitive sequences or complex architectures.
For companies involved in custom peptide synthesis, sourcing high-quality Fmoc-HomoArg(Pbf)-OH is a strategic imperative. Its application as a custom peptide synthesis chemical enables the creation of tailored peptide sequences designed to interact with specific biological targets. This capability accelerates the identification and optimization of lead compounds in drug discovery programs. By partnering with reliable manufacturers and suppliers of this essential amino acid derivative, research institutions and pharmaceutical companies can ensure the success of their demanding projects.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing a consistent supply of this high-purity peptide synthesis building block. Our commitment ensures that researchers have access to the quality materials needed to drive innovation in peptide drug discovery, contributing to the development of next-generation therapies. Proper handling and storage, including maintaining a cool environment at 0°C, are crucial for preserving the compound's optimal performance and purity.
Perspectives & Insights
Chem Catalyst Pro
“As a result, this Pbf protected homoarginine derivative is a preferred choice for synthesizing peptides with sensitive sequences or complex architectures.”
Agile Thinker 7
“For companies involved in custom peptide synthesis, sourcing high-quality Fmoc-HomoArg(Pbf)-OH is a strategic imperative.”
Logic Spark 24
“Its application as a custom peptide synthesis chemical enables the creation of tailored peptide sequences designed to interact with specific biological targets.”