The field of peptide synthesis is critical for advancements in pharmaceuticals and biotechnology. At the forefront of this innovation is the strategic use of specialized building blocks, and Fmoc-HomoArg(Pbf)-OH stands out as a key player. This compound, identified by its CAS number 401915-53-5, is an indispensable tool for researchers and manufacturers aiming for high-purity peptide synthesis.

Fmoc-HomoArg(Pbf)-OH serves as a crucial pharmaceutical intermediate, enabling the precise incorporation of homoarginine residues into growing peptide chains during solid-phase peptide synthesis (SPPS). The Fmoc (9H-fluoren-9-ylmethoxycarbonyl) group acts as a temporary protecting group for the alpha-amino function, allowing for controlled deprotection and subsequent coupling. Simultaneously, the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group effectively shields the guanidino side chain of homoarginine, preventing unwanted side reactions and ensuring the fidelity of the synthesized peptide sequence.

The reliability of this compound as a high purity peptide synthesis building block cannot be overstated. Its consistent quality, typically exceeding 98% purity, guarantees minimal contamination, which is paramount in pharmaceutical applications where even trace impurities can impact efficacy and safety. For those seeking a dependable supplier, sourcing this Pbf protected homoarginine from reputable manufacturers ensures adherence to stringent quality standards.

The application of Fmoc-HomoArg(Pbf)-OH extends to custom peptide synthesis projects. Whether developing novel therapeutic agents or creating peptide libraries for screening, this chemical is instrumental. Its role as an advanced Fmoc SPPS reagent facilitates the creation of complex peptides with specific biological activities, accelerating drug discovery efforts. The demand for such specialized amino acid derivatives underscores the growing sophistication of pharmaceutical research.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Fmoc-HomoArg(Pbf)-OH to support these critical endeavors. By ensuring the availability of this vital component, we empower scientists and developers to push the boundaries of pharmaceutical innovation. Understanding the properties and correct handling of this compound, such as proper storage at 0°C to maintain its integrity, is key to achieving successful synthesis outcomes. The journey from basic research to life-saving medication often relies on the quality of these fundamental chemical building blocks.