For professionals in the pharmaceutical sector, especially those involved in the synthesis of vital antibiotics like Moxifloxacin, obtaining high-quality intermediates is a critical aspect of their operation. This guide focuses on 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid (CAS: 112811-72-0), a key building block, and provides insights on where and how to buy it effectively.

Understanding the Intermediate: Specifications and Applications

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid is a white or off-white crystalline powder with a chemical formula C14H11F2NO4. Its primary application is as a crucial intermediate in the synthesis of Moxifloxacin hydrochloride and Moxifloxacin, which are widely used fluoroquinolone antibiotics. The compound boasts high purity, typically exceeding 99%, with stringent controls on impurities, ensuring its suitability for pharmaceutical manufacturing.

When seeking to procure this chemical, procurement managers and R&D scientists must pay close attention to:

  • Assay: Look for products with an assay of ≥98.0% or higher.
  • Impurity Profile: A low percentage of related substances and total impurities is crucial.
  • Physical Properties: Consistency in appearance and form aids in process control.
  • CAS Number Verification: Ensure the CAS number 112811-72-0 matches the product description.

Where to Source and Buy This Intermediate

Finding a reliable supplier for pharmaceutical intermediates is paramount. Many global pharmaceutical companies source such chemicals from specialized manufacturers. When looking to buy 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid, consider the following:

  • Dedicated Chemical Manufacturers: Companies specializing in pharmaceutical intermediates often offer the best combination of quality, price, and technical support. Many leading manufacturers are based in China.
  • Requesting Quotes: Always request a quote from potential suppliers to compare pricing and delivery terms. This is a standard practice for B2B chemical purchases.
  • Evaluating Supplier Credentials: Check for manufacturing certifications (like GMP, though often intermediates are supplied under less stringent but still controlled conditions), quality control documentation (CoAs), and responsiveness to inquiries.

As a dedicated manufacturer and supplier of high-quality pharmaceutical intermediates, we offer 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid to meet your production needs. We understand the importance of reliable sourcing for your critical API synthesis. We invite you to reach out for a quote to learn more about our competitive pricing and unwavering commitment to quality for your chemical procurement.