In the intricate world of pharmaceutical manufacturing, the quality of raw materials and intermediates directly impacts the safety and efficacy of the final drug product. For the synthesis of vital cancer therapeutics, such as Capecitabine, a key intermediate, 1,2,3-Triacetyl-5-deoxy-D-ribose (CAS 62211-93-2), plays an indispensable role. Understanding its properties and sourcing it from reliable manufacturers is a strategic imperative for any pharmaceutical company.

Understanding the Compound: Properties and Purity

1,2,3-Triacetyl-5-deoxy-D-ribose is a derivative of ribose, characterized by acetyl groups at the 1, 2, and 3 positions and a deoxy function at the 5 position. Typically appearing as a yellow to brown powder, it exhibits a melting point range of 63-64°C and a boiling point of 315°C. Crucially for pharmaceutical applications, its solubility in ethanol and other organic solvents makes it amenable to various reaction conditions. The most critical attribute for its use as a pharmaceutical intermediate is its purity. Suppliers commonly offer this compound with a purity of ≥98% (GC), which is essential for minimizing side reactions and ensuring the desired stereochemistry in subsequent synthesis steps.

The Critical Link: From Intermediate to API

The primary application of 1,2,3-Triacetyl-5-deoxy-D-ribose is as a precursor in the multi-step synthesis of Capecitabine. Capecitabine is an orally administered chemotherapy drug used to treat various types of cancer, including breast and colorectal cancer. The successful transformation of this intermediate into a high-quality Capecitabine API relies heavily on the quality and consistency of the starting material. Therefore, when pharmaceutical companies look to buy 1,2,3-Triacetyl-5-deoxy-D-ribose, they are not just purchasing a chemical; they are investing in the integrity of their final product.

Finding a Trusted Manufacturer and Supplier

Securing a stable and quality-assured supply chain for pharmaceutical intermediates requires due diligence. For those seeking a 1,2,3-Triacetyl-5-deoxy-D-ribose manufacturer, especially in competitive markets like China, several indicators point to a reliable partner:

  • ISO Certification: Companies adhering to ISO standards often demonstrate a commitment to quality management.
  • Technical Support: A supplier that can offer technical data sheets, safety information, and respond to queries promptly is invaluable.
  • Scalability: The ability to scale production from research quantities to commercial volumes is a significant advantage.
  • Competitive Pricing: Obtaining a price quote for CAS 62211-93-2 from multiple qualified suppliers allows for informed purchasing decisions.

Advantages of Sourcing from Established Chemical Suppliers

Partnering with a reputable chemical supplier for 1,2,3-Triacetyl-5-deoxy-D-ribose offers distinct benefits. It ensures that the product meets stringent purity specifications, complies with relevant safety standards, and is delivered reliably. Many suppliers also offer flexible payment terms and efficient logistics, facilitating seamless integration into your manufacturing workflow.

In summary, 1,2,3-Triacetyl-5-deoxy-D-ribose is more than just a chemical compound; it's a critical enabler in the production of life-saving medications. Pharmaceutical professionals are encouraged to prioritize quality and reliability when sourcing this essential intermediate, ensuring the continued development and availability of critical treatments.