In the intricate world of chemical manufacturing, the quality and reliability of intermediates are paramount to the success of downstream products. 2-(Dimethylphosphoryl)aniline, bearing the CAS number 1197953-47-1, stands out as a high-value chemical intermediate, particularly sought after for its role in pharmaceutical synthesis and its potential in various industrial applications. As a dedicated supplier, we focus on providing this compound with exceptional purity to meet the exacting standards of our clients.

Product Specifications and Chemical Properties

Our 2-(Dimethylphosphoryl)aniline is supplied with a guaranteed minimum purity of 98%, making it suitable for demanding synthesis processes. Its chemical formula is C8H12NOP, with a molecular weight of approximately 169.16 g/mol. While sources describe it as a pale yellow to brown liquid, its precise appearance and handling require adherence to standard laboratory and industrial safety protocols. The molecule's structure, combining an aniline group with a dimethylphosphoryl moiety, confers specific reactivity that chemists leverage for complex molecular assembly.

Critical Applications in the Pharmaceutical Industry

The most significant application of 2-(Dimethylphosphoryl)aniline is its indispensable role as a key intermediate in the synthesis of Brigatinib. Brigatinib is a life-saving targeted therapy drug used to treat specific types of non-small-cell lung cancer (NSCLC) by inhibiting the anaplastic lymphoma kinase (ALK). The phosphine oxide structure is a critical component contributing to Brigatinib's potency and selectivity. For pharmaceutical manufacturers and research institutions, securing a consistent and high-quality supply of this intermediate is vital for their drug development pipelines. We understand the importance of this link and are committed to being a reliable source.

Industrial Uses and Versatility

Beyond its critical role in oncology drug development, 2-(Dimethylphosphoryl)aniline exhibits versatility that extends to other industrial sectors. It serves as an intermediate in the production of certain organic pigments, where its chemical structure can contribute to unique color properties and enhanced stability in applications like coatings and plastics. Additionally, it functions as an inhibitor and stabilizer in various industrial processes, helping to ensure product quality and process efficiency by preventing unwanted chemical reactions. This broad utility makes it a valuable compound for diverse manufacturing needs.

Procuring 2-(Dimethylphosphoryl)aniline: Your Trusted Source

When seeking to purchase 2-(Dimethylphosphoryl)aniline, it is crucial to partner with a reputable supplier who prioritizes quality and reliability. As a manufacturer and supplier based in China, we are dedicated to providing this high-purity intermediate with excellent customer service and competitive pricing. We welcome inquiries from procurement managers and research scientists looking to buy this essential chemical. Contact us today to obtain a quote and sample, and discover how our commitment to quality can support your synthesis and manufacturing goals.