Advanced chemical synthesis is the bedrock of innovation across numerous industries, particularly in pharmaceuticals and materials science. Within this realm, specialized intermediates play a pivotal role, enabling the creation of complex molecules with targeted functionalities. 2-(Dimethylphosphoryl)aniline, known by its CAS number 1197953-47-1, stands out as a significant fine chemical intermediate with a growing range of applications. Understanding its chemical structure and reactivity is key for chemists aiming to develop cutting-edge products.

Chemical Profile and Properties

2-(Dimethylphosphoryl)aniline is characterized by its unique structure, incorporating both an aniline group and a dimethylphosphoryl group. This combination imparts specific reactivity, making it a versatile precursor in organic synthesis. While typically appearing as a pale yellow to brown liquid, its precise physical state can depend on purity and storage conditions. Its molecular formula is C8H12NOP, and it possesses a molecular weight of approximately 169.16 g/mol. The presence of the phosphine oxide moiety is particularly noteworthy, as it can influence the electronic and steric properties of molecules synthesized from it.

Applications in Organic Synthesis and Pigments

The primary application of 2-(Dimethylphosphoryl)aniline in advanced chemical synthesis is its use as a pharmaceutical intermediate. Its structural features are essential for building the complex architectures of modern drug molecules, such as the targeted cancer therapy Brigatinib. Beyond pharmaceuticals, this compound also serves as an intermediate in the production of certain organic pigments. These pigments are valued for their color fastness and stability, finding use in high-performance coatings, inks, and plastics. For manufacturers requiring these specialized intermediates, sourcing competitively priced materials is a strategic imperative.

Purchasing Considerations for Industrial Users

For industrial chemists and procurement specialists, the reliable supply of intermediates like 2-(Dimethylphosphoryl)aniline is critical. When considering where to buy, it is important to look for suppliers who can provide consistent purity (often specified as 98% min) and detailed technical data. We pride ourselves on being a reputable manufacturer and supplier, offering this compound to meet the demands of both research and industrial scale synthesis. We aim to provide competitive pricing for bulk purchases, making advanced chemistry more accessible.

The Advantage of Speciality Chemical Suppliers

Engaging with speciality chemical suppliers who focus on pharmaceutical intermediates and fine chemicals ensures access to expertise and quality products. Our company is dedicated to supporting the chemical synthesis community by offering compounds like 2-(Dimethylphosphoryl)aniline with high standards of quality and service. If you are looking to purchase this intermediate, we encourage you to request a quote or sample to evaluate our offerings and discover how we can contribute to your synthesis projects.