In the realm of chemical sourcing for research and industrial applications, precise specifications and clear understanding of a compound's utility are crucial. L-Norleucine, identified by CAS number 327-57-1, is a prime example of a chemical that requires detailed attention to its properties for effective utilization, particularly as a pharmaceutical intermediate or a component in advanced materials.

Detailed Specifications of L-Norleucine

L-Norleucine, also known as (S)-2-aminohexanoic acid, is characterized by a molecular formula of C6H13NO2 and a molecular weight of 131.17. Its physical properties are essential for understanding its handling and application:

  • Appearance: Typically presents as a white to off-white crystalline powder, indicating a solid form at room temperature.
  • Purity: Reputable suppliers offer L-Norleucine with an assay of 98.5% to 101.0%, signifying a high degree of purity vital for sensitive applications.
  • Solubility: It exhibits solubility in 3M-HCl, appearing as a colorless and clear solution at a specific concentration (c=4).
  • Specific Rotation: The specific optical rotation ([α]D20) is typically between +23.5° and +24.5° (c=4, 6M-HCl), confirming its chiral nature as the L-isomer.
  • Key Impurity Limits: Strict controls on loss on drying (≤0.3%), residue on ignition (≤0.1%), chloride (≤0.02%), sulfate (≤0.03%), heavy metals (≤10ppm), iron (≤10ppm), and arsenic (≤1ppm) are standard for high-grade material. The absence of other amino acids by TLC further emphasizes its quality.

Applications in the Chemical Industry

The primary application of L-Norleucine lies in its use as a pharmaceutical intermediate. Its structure as an amino acid derivative makes it a valuable building block for the synthesis of various active pharmaceutical ingredients (APIs) and complex organic molecules. Researchers also utilize it in biochemical studies and for creating novel amino acid derivatives that can lead to advancements in medicinal chemistry and material science.

Procuring L-Norleucine from Trusted Suppliers

For procurement professionals seeking to buy L-Norleucine, it is crucial to partner with manufacturers and suppliers who can guarantee these stringent specifications. When inquiring about price or requesting a quotation, it is advisable to confirm the detailed specifications, particularly the assay and impurity profiles, to ensure the material is suitable for your specific needs. A reliable supplier in China can offer competitive pricing for this high-quality chemical, supporting your research and manufacturing endeavors effectively.