High-Purity (S)-(+)-FMOC-TIC-OH: Supplier Insights from China
In the highly specialized field of pharmaceutical intermediates, precision and purity are non-negotiable. (S)-(+)-2-(9-Fluorenylmethoxycarbonyl)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid, identified by CAS 136030-33-6 and often abbreviated as Fmoc-Tic-OH, is a prime example of such a critical compound. This chiral building block is indispensable for researchers and manufacturers involved in complex organic synthesis, particularly in the development of novel pharmaceuticals and peptide-based therapeutics.
As a procurement specialist or R&D scientist, understanding the exact specifications of Fmoc-Tic-OH is vital. Its typical form is a white to off-white crystalline powder, with a melting point in the range of 146-149°C. The minimum purity often required is 95%, with higher purities (e.g., ≥98.5%) also available to meet stringent application demands. Crucially, its defined optical activity ([α]20/D +26.0±3.0° in methanol) confirms its specific enantiomeric form, which is essential for chiral synthesis.
When seeking to buy this specialized intermediate, many professionals turn to China for its robust chemical manufacturing sector. Sourcing Fmoc-Tic-OH from a trusted manufacturer in China, like NINGBO INNO PHARMCHEM CO.,LTD., offers distinct advantages. These include competitive pricing, significant production capacities, and access to a well-established supply chain. For bulk orders, understanding the lead times and reliability of a Chinese supplier is paramount.
The chemical properties of Fmoc-Tic-OH also make it highly adaptable for various synthetic processes. It is soluble in common organic solvents such as chloroform, dichloromethane, ethyl acetate, and DMSO, which are frequently used in laboratory settings and industrial-scale synthesis. Its utility in Fmoc solid-phase peptide synthesis is well-documented, where it serves as a key building block for introducing specific structural motifs into peptide chains.
For decision-makers evaluating the price of N-FMOC-L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, it is important to consider the total value proposition. This includes not only the unit cost but also the quality assurance, consistency, and the supplier's ability to provide timely delivery. A supplier with a proven track record in exporting pharmaceutical intermediates can navigate the complexities of international trade efficiently.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to being your go-to source for high-purity Fmoc-Tic-OH. We leverage our expertise as a leading China-based manufacturer and supplier to provide you with the essential chiral intermediates needed to drive your pharmaceutical research and development forward. When you need to purchase quality, reliability, and value, consider our comprehensive offerings.
Perspectives & Insights
Chem Catalyst Pro
“The chemical properties of Fmoc-Tic-OH also make it highly adaptable for various synthetic processes.”
Agile Thinker 7
“It is soluble in common organic solvents such as chloroform, dichloromethane, ethyl acetate, and DMSO, which are frequently used in laboratory settings and industrial-scale synthesis.”
Logic Spark 24
“Its utility in Fmoc solid-phase peptide synthesis is well-documented, where it serves as a key building block for introducing specific structural motifs into peptide chains.”