Peptide chemistry is a cornerstone of modern drug discovery and development, enabling the creation of therapeutics with high specificity and efficacy. Within this dynamic field, specialized building blocks are essential for constructing complex peptide sequences. One such valuable compound is (S)-(+)-2-(9-Fluorenylmethoxycarbonyl)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid (CAS: 136030-33-6), often referred to as Fmoc-Tic-OH.

As a key amino acid derivative, Fmoc-Tic-OH offers unique structural features that can introduce specific conformational constraints or functionalities into a peptide chain. Its incorporation can influence a peptide’s binding affinity, metabolic stability, and overall biological activity. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group is a standard in solid-phase peptide synthesis (SPPS) due to its facile removal under mild basic conditions, ensuring that the growing peptide chain remains intact.

For researchers and chemists engaged in peptide synthesis, the ability to buy Fmoc-Tic-OH from reliable sources is critical. The quality of the starting materials directly impacts the success of the synthesis and the purity of the final peptide product. When searching for this compound, it is important to consider suppliers who can guarantee high enantiomeric purity and chemical integrity, ensuring that the (S) configuration is precisely maintained. This is where a dedicated manufacturer in China, such as NINGBO INNO PHARMCHEM CO.,LTD., can be a valuable partner.

The application of Fmoc-Tic-OH extends beyond basic peptide elongation. It is employed in the synthesis of peptidomimetics, cyclic peptides, and peptides with modified backbones, offering chemists advanced tools to design molecules with tailored pharmacological properties. Its specific chemical properties, such as its solubility in common organic solvents like DMF, DMSO, and dichloromethane, further facilitate its integration into standard SPPS protocols.

Procurement managers looking to source this specialized intermediate will often compare price points and availability from various suppliers. While cost is a factor, it should be balanced against quality assurance. A supplier that provides detailed specifications, including melting point (146-149°C), molecular weight (399.44 g/mol), and clear storage instructions (2-8°C), demonstrates a commitment to product integrity.

When you need to purchase Fmoc-Tic-OH, looking for a manufacturer that understands the stringent requirements of pharmaceutical research is crucial. NINGBO INNO PHARMCHEM CO.,LTD. stands ready to support your peptide synthesis projects with high-quality Fmoc-Tic-OH, offering a consistent and dependable supply from our China operations. We empower your research by providing the essential chiral building blocks you need for innovation.