The pharmaceutical industry relies heavily on a diverse array of chemical intermediates to synthesize life-saving medications. Among these, organoboron compounds, particularly boronic acids, have gained immense prominence due to their synthetic utility. This article focuses on 4-Carboxy-3-fluorophenylboronic acid (CAS 120153-08-4), a key intermediate that facilitates complex organic synthesis and is vital for drug development. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer in China, supplies this high-quality compound to the global market.

4-Carboxy-3-fluorophenylboronic acid is characterized by its molecular formula C7H6BFO4 and a molecular weight of 183.93 g/mol. It typically presents as a white powder, with a melting point in the range of 236-240°C. The compound's solubility in water adds to its ease of handling and application in various chemical processes. Its structure, which includes a carboxylic acid group, a fluorine atom, and a boronic acid group, makes it a powerful building block in organic synthesis. The fluorine atom, in particular, is often incorporated into drug molecules to enhance their pharmacological properties, such as improving metabolic stability and increasing lipophilicity, which can lead to better drug absorption and efficacy.

The primary application driving the demand for 4-Carboxy-3-fluorophenylboronic acid is its use as a pharmaceutical intermediate. It is a key reactant in Suzuki-Miyaura cross-coupling reactions, a widely used method for creating carbon-carbon bonds, essential for assembling intricate drug molecules. This capability allows for the precise introduction of the fluorinated benzoic acid moiety into potential drug candidates. For researchers and manufacturers needing to buy this compound, its high purity, often specified at ≥98.0%, is critical for achieving consistent and predictable reaction yields and product quality. Relying on established suppliers ensures that the specifications meet the stringent requirements of pharmaceutical research and production.

The versatility of 4-Carboxy-3-fluorophenylboronic acid extends to its potential use in the synthesis of agrochemicals and advanced materials, further underscoring its importance. Its dual functionality allows for complex molecular constructions, paving the way for innovation in multiple chemical sectors. For companies seeking to source this essential intermediate, partnering with a reputable manufacturer in China like NINGBO INNO PHARMCHEM CO.,LTD. offers significant advantages. These include competitive pricing, stringent quality control, and reliable supply chain management, all crucial for the timely progression of pharmaceutical research and manufacturing projects. The ability to purchase this chemical with confidence directly impacts the efficiency and success of drug development pipelines.