The Role of 4-Carboxy-3-fluorophenylboronic Acid in Modern Pharmaceutical Development
In the dynamic landscape of pharmaceutical research and development, the availability of high-quality chemical intermediates is paramount. Among these essential building blocks, 4-Carboxy-3-fluorophenylboronic acid (CAS 120153-08-4) has emerged as a compound of significant interest. Its unique chemical structure, featuring both a carboxylic acid group and a boronic acid moiety on a fluorinated phenyl ring, makes it an invaluable reagent for a wide array of synthetic transformations. As a trusted manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying this critical material to researchers and manufacturers worldwide.
The primary application of 4-Carboxy-3-fluorophenylboronic acid lies in its use as a pharmaceutical intermediate. It serves as a versatile synthon in the construction of complex organic molecules that form the backbone of many modern pharmaceuticals. The boronic acid functional group is particularly well-suited for Suzuki-Miyaura cross-coupling reactions, a Nobel Prize-winning methodology that allows for the efficient formation of carbon-carbon bonds. This capability is crucial for assembling intricate drug molecules with precise stereochemistry and desired pharmacological activity. Researchers often seek out this compound to facilitate the synthesis of novel drug candidates targeting various diseases, leveraging the specific reactivity offered by its fluorinated aromatic ring.
Beyond its role in drug discovery, 4-Carboxy-3-fluorophenylboronic acid also finds applications in materials science and other areas of fine chemical synthesis. The carboxylic acid group provides an additional handle for further functionalization or conjugation, while the fluorine atom can impart desirable properties such as increased metabolic stability and lipophilicity to the final product. These characteristics are highly sought after in the development of advanced materials and specialized organic compounds. For those looking to purchase this compound, understanding its specifications, such as its typical assay of 98.0% or higher and its white powder appearance, is vital for ensuring optimal reaction performance. The solubility in water further enhances its utility in various reaction media. Companies aiming to buy this chemical often look for reliable suppliers who can guarantee consistent quality and timely delivery, underscoring the importance of sourcing from established manufacturers.
The strategic advantage of sourcing from a Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. includes competitive pricing and a robust supply chain. We understand the critical nature of these intermediates for our clients' research and production timelines. Therefore, we focus on maintaining high standards of quality control and efficient logistics. Whether you are engaged in early-stage drug discovery or large-scale manufacturing, our commitment is to provide you with the high-purity 4-Carboxy-3-fluorophenylboronic acid needed to drive your projects forward. Exploring the potential of this compound is a step towards innovative solutions in chemistry and medicine.
Perspectives & Insights
Alpha Spark Labs
“We understand the critical nature of these intermediates for our clients' research and production timelines.”
Future Pioneer 88
“Therefore, we focus on maintaining high standards of quality control and efficient logistics.”
Core Explorer Pro
“Whether you are engaged in early-stage drug discovery or large-scale manufacturing, our commitment is to provide you with the high-purity 4-Carboxy-3-fluorophenylboronic acid needed to drive your projects forward.”