The pharmaceutical industry relies heavily on a robust supply of high-quality chemical intermediates to drive the development and production of life-saving medicines. Among these vital components, 2-Amino-5-bromopyridin-3-ol (CAS: 39903-01-0) holds significant importance. As a dedicated manufacturer in China, we recognize the strategic value of this compound and are committed to providing a reliable source for the global pharmaceutical sector.

What is 2-Amino-5-bromopyridin-3-ol?

2-Amino-5-bromopyridin-3-ol is a substituted pyridine derivative characterized by its unique arrangement of functional groups: an amino group, a bromine atom, and a hydroxyl group. This specific configuration provides it with a rich chemical reactivity, making it an ideal starting material or intermediate in the synthesis of more complex molecules.

Key Roles as a Pharmaceutical Intermediate

The versatility of 2-Amino-5-bromopyridin-3-ol makes it indispensable in several pharmaceutical applications:

  • Synthesis of Active Pharmaceutical Ingredients (APIs): Its structure serves as a core scaffold or a crucial fragment in the creation of many APIs. The bromine atom, in particular, is an excellent handle for introducing diverse functionalities through various cross-coupling reactions, enabling the construction of complex drug molecules.
  • Development of Kinase Inhibitors: This intermediate is frequently employed in the synthesis of potent kinase inhibitors used in targeted cancer therapies. Its ability to form key hydrogen bonds within the ATP-binding pocket of kinases is a major advantage in drug design.
  • Building Block for Novel Drug Candidates: Researchers utilize this compound to explore new chemical entities for a wide range of therapeutic areas, leveraging its structure for lead optimization and SAR studies.

Manufacturing and Sourcing Considerations

Producing 2-Amino-5-bromopyridin-3-ol requires precise synthetic methodologies and stringent quality control. Common synthesis routes involve bromination of pyridinol precursors or multi-step transformations starting from more basic pyridine derivatives. Ensuring high purity (>97%) is paramount for its use in pharmaceutical manufacturing, as impurities can compromise the efficacy and safety of the final drug product.

As a leading pharmaceutical intermediate manufacturer in China, we focus on:

  • Optimized Synthesis Routes: Employing efficient and scalable production methods to ensure consistent product quality and competitive pricing.
  • Rigorous Quality Control: Implementing comprehensive analytical testing (NMR, HPLC, GC-MS) to guarantee the purity and identity of each batch.
  • Reliable Supply Chain: Maintaining adequate stock and efficient logistics to meet the demands of our global clientele.

Why Choose Us as Your Supplier?

When you need to 'buy 2-amino-5-bromopyridin-3-ol' or seek a '2-amino-5-bromopyridin-3-ol manufacturer' with a proven track record, consider our expertise. We offer:

  • High Purity Products: Guaranteed purity levels essential for pharmaceutical R&D and manufacturing.
  • Competitive Pricing: Especially for bulk orders, we provide cost-effective solutions.
  • Technical Support: Our team can assist with inquiries regarding specifications and applications.
  • Global Reach: We export to pharmaceutical companies worldwide, ensuring timely and compliant delivery.

Inquire with us for your requirements of 2-Amino-5-bromopyridin-3-ol. We are dedicated to supporting the pharmaceutical industry with high-quality intermediates that drive innovation and improve patient outcomes.