The Importance of Specialty Amino Acids: Focus on Fmoc-HomoArg(Pbf)-OH
The realm of pharmaceutical innovation is heavily reliant on the precise manipulation of molecular structures, and specialty amino acids serve as fundamental building blocks in this endeavor. Among these critical components, Fmoc-HomoArg(Pbf)-OH stands out as a key player, facilitating advanced peptide synthesis and contributing to the development of novel therapeutics. Identified by its CAS number 401915-53-5, this compound embodies the precision and quality demanded by the modern chemical industry.
Fmoc-HomoArg(Pbf)-OH is a highly functionalized amino acid derivative that plays a crucial role as a pharmaceutical intermediate. Its primary application lies in peptide synthesis, specifically within the context of Fmoc solid-phase peptide synthesis (SPPS). The compound’s structure is engineered with the Fmoc (9H-fluoren-9-ylmethoxycarbonyl) group for efficient N-terminal protection and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group for safeguarding the homoarginine side chain. This strategic design ensures controlled elongation of peptide chains, minimizing side reactions and maximizing the purity of the final product.
The significance of this Pbf protected homoarginine derivative extends to its role as a high-purity peptide synthesis building block. Researchers and manufacturers rely on its consistent quality, typically exceeding 98% purity, to ensure the integrity and efficacy of their peptide-based products. Whether for drug discovery, diagnostic tools, or biomaterials, the purity of such intermediates is paramount.
The ability to perform custom peptide synthesis with reliability hinges on the availability of advanced Fmoc SPPS reagents like Fmoc-HomoArg(Pbf)-OH. Its specific properties allow scientists to construct complex peptide sequences with greater accuracy, thereby accelerating the discovery and development of new therapeutic agents. This makes it a vital component in the pipeline for creating next-generation medicines.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing access to these essential specialty amino acids. By ensuring a steady supply of high-quality Fmoc-HomoArg(Pbf)-OH, we aim to support the ongoing advancements in pharmaceutical research and biotechnology. Proper storage at 0°C is critical for maintaining the compound's stability and reactivity, emphasizing the need for careful handling and management in laboratory and production environments.
The continuous demand for sophisticated chemical building blocks highlights the dynamic nature of pharmaceutical science and the critical role that specialized amino acids play in driving innovation.
Fmoc-HomoArg(Pbf)-OH is a highly functionalized amino acid derivative that plays a crucial role as a pharmaceutical intermediate. Its primary application lies in peptide synthesis, specifically within the context of Fmoc solid-phase peptide synthesis (SPPS). The compound’s structure is engineered with the Fmoc (9H-fluoren-9-ylmethoxycarbonyl) group for efficient N-terminal protection and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group for safeguarding the homoarginine side chain. This strategic design ensures controlled elongation of peptide chains, minimizing side reactions and maximizing the purity of the final product.
The significance of this Pbf protected homoarginine derivative extends to its role as a high-purity peptide synthesis building block. Researchers and manufacturers rely on its consistent quality, typically exceeding 98% purity, to ensure the integrity and efficacy of their peptide-based products. Whether for drug discovery, diagnostic tools, or biomaterials, the purity of such intermediates is paramount.
The ability to perform custom peptide synthesis with reliability hinges on the availability of advanced Fmoc SPPS reagents like Fmoc-HomoArg(Pbf)-OH. Its specific properties allow scientists to construct complex peptide sequences with greater accuracy, thereby accelerating the discovery and development of new therapeutic agents. This makes it a vital component in the pipeline for creating next-generation medicines.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing access to these essential specialty amino acids. By ensuring a steady supply of high-quality Fmoc-HomoArg(Pbf)-OH, we aim to support the ongoing advancements in pharmaceutical research and biotechnology. Proper storage at 0°C is critical for maintaining the compound's stability and reactivity, emphasizing the need for careful handling and management in laboratory and production environments.
The continuous demand for sophisticated chemical building blocks highlights the dynamic nature of pharmaceutical science and the critical role that specialized amino acids play in driving innovation.
Perspectives & Insights
Future Origin 2025
“The compound’s structure is engineered with the Fmoc (9H-fluoren-9-ylmethoxycarbonyl) group for efficient N-terminal protection and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group for safeguarding the homoarginine side chain.”
Core Analyst 01
“This strategic design ensures controlled elongation of peptide chains, minimizing side reactions and maximizing the purity of the final product.”
Silicon Seeker One
“The significance of this Pbf protected homoarginine derivative extends to its role as a high-purity peptide synthesis building block.”