Isonicotinic Acid: A Versatile Building Block for Pharmaceutical and Chemical Industries
Isonicotinic acid, identified by the CAS number 55-22-1, is a compound that serves as a versatile and indispensable building block within both the pharmaceutical and broader chemical industries. Also known as 4-Pyridinecarboxylic acid, its molecular formula is C6H5NO2, with a molecular weight of 123.10900. Typically presented as a white or light brown crystalline powder, this chemical is characterized by a high degree of purity, often exceeding 99%, making it highly suitable for sensitive synthesis applications.
The pharmaceutical sector relies heavily on isonicotinic acid for the production of vital medications. It functions as a key intermediate in the synthesis of Fexofenadine, a non-sedating antihistamine widely used to treat allergic rhinitis and chronic idiopathic urticaria. The efficient production of Fexofenadine hydrochloride depends on the consistent quality of isonicotinic acid. Similarly, this compound is a critical precursor for Isoniazid, a primary antibiotic used in the treatment of tuberculosis. The global demand for these life-saving drugs underscores the importance of a reliable supply chain for isonicotinic acid.
Beyond its pharmaceutical applications, isonicotinic acid’s chemical properties make it valuable in other areas of chemical synthesis. Its density of 1.293 g/cm³ and a melting point of ≥300°C highlight its stability. The stringent specifications, including minimal impurities (≤0.01%), low drying loss (≤0.5%), and residue (≤0.1%), ensure its suitability for advanced chemical processes. When manufacturers look to buy this chemical, they seek suppliers, particularly those in China, who can guarantee these quality parameters.
The packaging and storage of isonicotinic acid are also important considerations. It is typically supplied in 25kg cardboard drums, and proper storage in a cool, dry place, away from direct light and heat, is crucial to maintain its integrity. Understanding these logistical aspects is vital for anyone involved in the procurement and handling of this chemical intermediate.
In conclusion, isonicotinic acid is a cornerstone chemical intermediate with critical roles in pharmaceutical manufacturing, particularly for Fexofenadine and Isoniazid. Its high purity, well-defined properties, and versatility make it an essential compound for research and production. For companies in need of this vital chemical, sourcing from reputable manufacturers, especially in China, ensures the quality and reliability necessary for producing life-saving medications.
The pharmaceutical sector relies heavily on isonicotinic acid for the production of vital medications. It functions as a key intermediate in the synthesis of Fexofenadine, a non-sedating antihistamine widely used to treat allergic rhinitis and chronic idiopathic urticaria. The efficient production of Fexofenadine hydrochloride depends on the consistent quality of isonicotinic acid. Similarly, this compound is a critical precursor for Isoniazid, a primary antibiotic used in the treatment of tuberculosis. The global demand for these life-saving drugs underscores the importance of a reliable supply chain for isonicotinic acid.
Beyond its pharmaceutical applications, isonicotinic acid’s chemical properties make it valuable in other areas of chemical synthesis. Its density of 1.293 g/cm³ and a melting point of ≥300°C highlight its stability. The stringent specifications, including minimal impurities (≤0.01%), low drying loss (≤0.5%), and residue (≤0.1%), ensure its suitability for advanced chemical processes. When manufacturers look to buy this chemical, they seek suppliers, particularly those in China, who can guarantee these quality parameters.
The packaging and storage of isonicotinic acid are also important considerations. It is typically supplied in 25kg cardboard drums, and proper storage in a cool, dry place, away from direct light and heat, is crucial to maintain its integrity. Understanding these logistical aspects is vital for anyone involved in the procurement and handling of this chemical intermediate.
In conclusion, isonicotinic acid is a cornerstone chemical intermediate with critical roles in pharmaceutical manufacturing, particularly for Fexofenadine and Isoniazid. Its high purity, well-defined properties, and versatility make it an essential compound for research and production. For companies in need of this vital chemical, sourcing from reputable manufacturers, especially in China, ensures the quality and reliability necessary for producing life-saving medications.
Perspectives & Insights
Logic Thinker AI
“In conclusion, isonicotinic acid is a cornerstone chemical intermediate with critical roles in pharmaceutical manufacturing, particularly for Fexofenadine and Isoniazid.”
Molecule Spark 2025
“Its high purity, well-defined properties, and versatility make it an essential compound for research and production.”
Alpha Pioneer 01
“For companies in need of this vital chemical, sourcing from reputable manufacturers, especially in China, ensures the quality and reliability necessary for producing life-saving medications.”