The landscape of chemical manufacturing and research is built upon a foundation of reliable, high-quality intermediates. 2-(2-Amino-5-bromobenzoyl) Pyridine, identified by its CAS number 1563-56-0, is a pivotal organic compound frequently sought after by professionals in the pharmaceutical and chemical synthesis industries. This article aims to provide a comprehensive overview of this chemical, its properties, its significance in synthetic pathways, and how to procure it effectively from trusted sources.

Chemical Identity and Key Properties

2-(2-Amino-5-bromobenzoyl) Pyridine is a compound that typically presents as a yellow solid. Its chemical structure, defined by the molecular formula C12H9BrN2O, features a distinct arrangement of a brominated phenyl group linked via a carbonyl to a pyridine ring. This structural configuration renders it a valuable precursor in various chemical transformations. Common specifications include a high purity level, often ≥98%, which is critical for its intended applications. Its melting point and solubility characteristics are also important factors for chemists when designing reaction conditions.

Applications and Significance in Synthesis

The primary application of 2-(2-Amino-5-bromobenzoyl) Pyridine is its indispensable role as an intermediate in the synthesis of Bromazepam. Bromazepam is a well-established pharmaceutical agent belonging to the benzodiazepine class, utilized for its anxiolytic, sedative, and muscle relaxant properties. The synthesis of Bromazepam from this intermediate involves specific, controlled chemical reactions that rely on its precise molecular structure and purity. Beyond pharmaceutical manufacturing, it serves as a versatile building block for chemists engaged in general organic synthesis, facilitating the creation of a wide array of complex organic molecules and specialty chemicals. Its utility in research and development for exploring new chemical entities is significant.

Where to Buy: Sourcing Strategies

Procuring 2-(2-Amino-5-bromobenzoyl) Pyridine efficiently requires a strategic approach to sourcing. The global market offers numerous avenues, with a strong presence of manufacturers and suppliers based in China, a hub for chemical production.

  • Identify Reliable Manufacturers: Direct engagement with manufacturers, particularly those specializing in pharmaceutical intermediates, is often the most effective way to secure high-quality products at competitive prices. Requesting a price quote is a standard initial step.
  • Supplier Due Diligence: Before making a purchase, it is crucial to vet suppliers. Look for companies with established reputations, quality certifications, and a history of providing necessary documentation such as Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS).
  • Consider Bulk Orders: For industrial applications, placing bulk orders with a trusted manufacturer can lead to significant cost savings and ensure supply chain stability.
  • Global Distribution Networks: Numerous chemical distributors worldwide also stock this intermediate, providing accessibility for diverse geographical locations and varying order sizes.

In summary, 2-(2-Amino-5-bromobenzoyl) Pyridine (CAS 1563-56-0) is a high-value chemical intermediate vital for the pharmaceutical industry and broader organic synthesis. By understanding its properties and employing sound sourcing practices, businesses can ensure access to this critical compound, thereby supporting innovation and production in their respective fields.