The pharmaceutical industry relies heavily on precisely manufactured intermediates to produce life-saving medications. 4-Nitroisoindolin-1-one (CAS 366452-97-3) stands out as a crucial component, particularly in the synthesis of Lenalidomide. For R&D scientists and procurement managers, understanding its key characteristics and application is fundamental to successful drug development and production.

Chemical Profile: 4-Nitroisoindolin-1-one

This chemical intermediate is characterized by its specific molecular formula and weight, which are critical for stoichiometric calculations in synthesis. Typically presented as a white to light yellow powder, its appearance is a visual indicator of its quality and purity. A high assay value, commonly specified as ≥98.0%, is essential for pharmaceutical applications to minimize by-products and ensure the efficacy of the final API. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. offer this product, ensuring it meets these stringent quality demands.

The Critical Link: Lenalidomide Synthesis

The primary application of 4-Nitroisoindolin-1-one is its role as a precursor in the synthesis of Lenalidomide, an immunomodulatory drug with significant therapeutic applications. The precise chemical transformations that convert 4-Nitroisoindolin-1-one into Lenalidomide are complex, requiring intermediates of unwavering quality. Therefore, sourcing from a reliable 4-Nitroisoindolin-1-one supplier is not just about acquiring a chemical; it's about ensuring the integrity of your downstream manufacturing process.

Procurement Insights for Buyers

When looking to purchase 4-Nitroisoindolin-1-one, especially for commercial use, buyers should prioritize suppliers who can demonstrate consistent product quality and a secure supply chain. Factors such as packaging (commonly 25 kg/drum), lot-to-lot consistency, and detailed Certificates of Analysis (CoA) are important considerations. Companies seeking to secure their supply of this intermediate should look for 4-Nitroisoindolin-1-one manufacturers that offer competitive pricing alongside robust quality assurance. Inquiries regarding 4-Nitroisoindolin-1-one price should always be coupled with an assessment of the supplier's overall reliability and capacity to meet demand.

A well-established 4-Nitroisoindolin-1-one manufacturer in China can often provide significant advantages in terms of cost-effectiveness and production scale. However, due diligence is key to selecting a partner that aligns with your company's quality and regulatory standards. By focusing on these aspects, researchers and manufacturers can ensure they are obtaining a high-quality intermediate that supports the successful production of Lenalidomide and other vital pharmaceuticals.