For synthetic chemists and medicinal chemists, access to well-characterized and high-purity compounds is the bedrock of successful research. NU 2058 (CAS: 161058-83-9), a guanine derivative, presents a fascinating case study in leveraging specific molecular properties for targeted therapeutic research, particularly in the area of cyclin-dependent kinase (CDK) inhibition. Its dual role as a direct inhibitor and a synthetic intermediate makes it a valuable asset in the chemist's toolkit.

Chemically, NU 2058 is recognized for its potent inhibitory activity against CDK1 and CDK2. This mechanism of action is crucial for understanding and manipulating cell cycle progression, a fundamental process often dysregulated in oncogenesis. The compound's structure, featuring a cyclohexylmethoxy group attached to a purine core, contributes to its binding affinity and inhibitory potency. For chemists involved in drug discovery, this molecule offers a starting point for structure-activity relationship (SAR) studies, aiming to design even more selective and effective CDK inhibitors.

The utility of NU 2058 extends to its role as a key intermediate in the synthesis of other significant compounds, notably NU 6140. This synthetic pathway is vital for researchers aiming to develop next-generation therapeutics with improved pharmacological profiles. When chemists look to buy NU 2058, they often seek assurance of its purity and form, typically a white powder with a melting point around 199°C. Partnering with a reliable manufacturer who can provide consistent quality is paramount for reproducible synthetic routes and reliable biological assays.

For any chemist or procurement specialist sourcing this compound, understanding where to find a dependable supplier is key. The competitive market for chemical reagents means that many options exist, but quality and reliability should be the primary considerations. Exploring options from established manufacturers in China can often yield high-purity grades at competitive prices, especially when considering bulk purchases for larger projects or scale-up synthesis.

In essence, NU 2058 represents more than just a chemical entity; it's a critical research tool and synthetic building block. Chemists who understand its properties and potential can effectively integrate it into their research programs. When you're ready to purchase NU 2058 for your laboratory, ensure you choose a supplier that aligns with your commitment to scientific rigor and quality.