In the intricate landscape of cancer research, understanding and targeting the cell cycle is paramount. Cyclin-dependent kinases (CDKs) play a pivotal role in regulating this process, and their dysregulation is a hallmark of many cancers. This has led to the development of CDK inhibitors as a promising therapeutic strategy. Among these, NU 2058 (CAS: 161058-83-9) stands out as a potent inhibitor of CDK1 and CDK2, offering valuable tools for scientists and researchers.

NU 2058, a guanine-based compound, has demonstrated significant efficacy in arresting cell cycling within cancer cells. Its ability to inhibit specific kinases like CDK1 and CDK2, with reported IC50 values in the micromolar range, makes it a critical molecule for studying the molecular mechanisms of cancer progression. Furthermore, NU 2058 serves as a key intermediate in the synthesis of other targeted therapies, such as NU 6140, which exhibits enhanced selectivity against CDK2-cyclin A. This makes it an indispensable component in the drug discovery pipeline for pharmaceutical companies.

For researchers and procurement managers seeking high-quality chemical intermediates, sourcing NU 2058 from a reputable manufacturer is essential. A reliable supplier ensures the purity and consistency of the compound, which are critical for reproducible scientific outcomes. When looking to buy NU 2058, prioritizing suppliers who provide detailed specifications, batch analysis reports, and adhere to stringent quality control measures is crucial. The availability of this compound from leading manufacturers in China offers a competitive advantage for global research initiatives.

The application of NU 2058 extends beyond basic research; it plays a vital role in the development of new anti-cancer drugs. By understanding how NU 2058 interacts with its targets and influences cellular pathways, scientists can design more effective treatments with fewer side effects. This molecule's contribution to understanding cell cycle arrest at the G2-M phase and its role in potentiating other therapeutic effects, like that of paclitaxel, underscores its importance.

For those in the pharmaceutical industry and academic research, securing a consistent and high-quality supply of NU 2058 is a strategic imperative. We, as a dedicated supplier, are committed to providing researchers with the essential building blocks they need to advance their work. Exploring options to purchase NU 2058 in various quantities, from research-scale to bulk requirements, is straightforward with our accessible services. Inquire about NU 2058 price and availability to support your next breakthrough.