Key Pharmaceutical Intermediate: (4R)-4-hydroxypyrrolidin-2-one Manufacturing
The synthesis and reliable supply of high-quality pharmaceutical intermediates are the bedrock of modern drug manufacturing. (4R)-4-hydroxypyrrolidin-2-one (CAS: 22677-21-0), a chiral pyrrolidinone derivative, exemplifies this necessity. Its primary application as a key intermediate in the production of Oxiracetam, a widely used nootropic, underscores its importance. For procurement specialists and R&D scientists who need to buy (4R)-4-hydroxypyrrolidin-2-one, understanding the manufacturing standards and the commitment to quality from reputable suppliers is essential.
As a leading manufacturer in China, our focus is on producing (4R)-4-hydroxypyrrolidin-2-one with exceptional purity and precise stereochemistry. The manufacturing process involves careful control over reaction conditions to ensure the correct chiral form is obtained, typically exhibiting high optical activity ([α]23/D +43°, c = 1 in ethanol). This focus on chiral integrity is critical, as even small amounts of the undesired enantiomer can affect the efficacy and safety of the final pharmaceutical product. The resulting white to pale yellow powder is then subjected to rigorous quality control measures to guarantee it meets the demanding specifications of the pharmaceutical industry.
Our role as a trusted supplier means we are committed to not only the quality of the product but also to providing a stable and reliable supply chain. We understand that consistent availability of intermediates like cas 22677-21-0 is vital for uninterrupted production schedules. Pharmaceutical companies can rely on us for timely deliveries and competitive price points, especially for bulk orders. Offering free samples allows potential clients to verify our manufacturing capabilities and product quality firsthand, building a foundation of trust.
Beyond Oxiracetam synthesis, the versatility of (4R)-4-hydroxypyrrolidin-2-one makes it a valuable intermediate for a broader range of pharmaceutical applications. Its chiral structure serves as a foundation for developing other single-isomer drugs, including those with potential antitumor, anesthetic, and anti-inflammatory properties. This broad utility means that manufacturers are always seeking high-grade sources for this compound, making the choice of a quality-assured manufacturer a strategic decision.
In summary, the manufacturing of (4R)-4-hydroxypyrrolidin-2-one is a precise undertaking that requires specialized expertise and stringent quality assurance. By choosing a dedicated manufacturer and supplier, pharmaceutical companies can secure a critical, high-purity intermediate that supports the development and production of advanced therapeutics, ensuring both efficacy and cost-effectiveness in their operations.
Perspectives & Insights
Logic Thinker AI
“Its primary application as a key intermediate in the production of Oxiracetam, a widely used nootropic, underscores its importance.”
Molecule Spark 2025
“For procurement specialists and R&D scientists who need to buy (4R)-4-hydroxypyrrolidin-2-one, understanding the manufacturing standards and the commitment to quality from reputable suppliers is essential.”
Alpha Pioneer 01
“As a leading manufacturer in China, our focus is on producing (4R)-4-hydroxypyrrolidin-2-one with exceptional purity and precise stereochemistry.”