In the realm of organic chemistry and pharmaceutical development, the stereochemistry of molecules can dictate their function, efficacy, and safety. Amino acids, the building blocks of proteins, are a prime example where chirality plays a critical role. Often, only one enantiomer of an amino acid exhibits the desired biological activity, while the other might be inactive or even detrimental. Therefore, accurately determining the enantiomeric purity of amino acids is a fundamental aspect of quality control and research in the pharmaceutical and biotechnology sectors. (S)-2-(5-fluoro-2,4-dinitrophenyl)amino)propanamide, or FDAA, is a leading reagent designed for this precise purpose.

FDAA serves as a chiral derivatizing agent, meaning it reacts with amino acids to form new compounds that are easier to analyze for their chiral composition. The process involves reacting FDAA with a sample containing amino acids, typically in an aqueous or mixed solvent system. The reagent's dinitrophenyl group provides a chromophore, making the resulting derivatives detectable via UV-Vis spectroscopy, which is standard in HPLC systems. More importantly, the inherent chirality of FDAA, combined with the amino acid, creates diastereomeric derivatives that exhibit distinct chromatographic behaviors.

When procurement managers or research scientists search for this compound, they are often looking for a reliable manufacturer who can supply it at a competitive price, ensuring consistent purity. As a dedicated manufacturer and supplier in China, we specialize in producing high-quality FDAA (CAS 95713-52-3) for demanding analytical applications. Our product is optimized for use in HPLC, facilitating the separation of D- and L-amino acid derivatives. This enables the precise calculation of enantiomeric excess (e.e.), a key metric for validating the stereochemical outcome of synthesis or for assessing the chiral composition of natural products.

The utility of FDAA extends to various analytical challenges, including the characterization of peptides, the quality assessment of chiral drug intermediates, and the study of metabolic pathways involving specific amino acid enantiomers. Its effectiveness lies in its reliable reactivity and the significant difference in retention times it imparts to the resulting diastereomers, leading to clear baseline separations on standard HPLC columns. This makes it an accessible and powerful tool for laboratories of all sizes.

For those seeking to purchase FDAA, understanding its role and the importance of sourcing from a reputable supplier is key to achieving accurate and reproducible results. We provide comprehensive support, including technical specifications and sample availability, to ensure you can confidently integrate our product into your analytical workflows. Contact us to buy FDAA or to request a quote, and enhance your capabilities in chiral amino acid analysis today.