In the intricate world of organic synthesis, the availability of high-quality, reliable intermediates is paramount. Among these crucial building blocks, 5-Bromoisophthalonitrile stands out for its versatility and wide-ranging applications. This article is designed for procurement managers, research scientists, and formulation chemists who seek to understand and source this vital chemical. We will delve into its properties, synthesis, applications, and importantly, how to efficiently procure it from reputable suppliers.

Understanding 5-Bromoisophthalonitrile: Properties and Significance

5-Bromoisophthalonitrile, identified by CAS number 160892-07-9, is an aromatic organic compound characterized by a benzene ring substituted with two nitrile groups (-CN) at the 1 and 3 positions and a bromine atom at the 5 position. Its molecular formula is C8H3BrN2, with a molecular weight of approximately 207.03 g/mol. Typically appearing as a white to yellow solid, its purity is a critical factor for its performance in downstream reactions. The presence of both nitrile groups and a reactive bromine atom makes it an exceptionally useful synthon.

The significance of 5-Bromoisophthalonitrile lies in its ability to act as a precursor in the synthesis of a diverse array of complex molecules. It is particularly valued in the fields of:

  • Pharmaceutical Intermediates: As a key building block, it facilitates the creation of active pharmaceutical ingredients (APIs) and advanced drug candidates.
  • Agrochemicals: Its structure lends itself to the development of novel pesticides, herbicides, and fungicides, contributing to agricultural innovation.
  • Advanced Materials: It serves as a critical monomer or linker in the synthesis of Metal-Organic Frameworks (MOFs) and Covalent Organic Frameworks (COFs), materials with exceptional properties for gas storage, separation, and catalysis.

Efficient Synthesis and Sourcing Strategies

The synthesis of 5-Bromoisophthalonitrile typically involves bromination reactions of isophthalonitrile. Common methods include direct bromination using bromine (Br2) in the presence of Lewis acid catalysts like iron(III) bromide (FeBr3), or using N-Bromosuccinimide (NBS) in polar solvents. The Sandmeyer reaction, starting from an amino-substituted precursor, also offers a route to this compound. For industrial-scale production, optimizing these methods for yield, purity, and cost-effectiveness is essential. Manufacturers focus on rigorous quality control to ensure the final product meets stringent specifications.

When looking to buy 5-Bromoisophthalonitrile, it is crucial to identify reliable manufacturers and suppliers. As a leading chemical supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-purity 5-Bromoisophthalonitrile. We understand the importance of supply chain stability and product consistency for our clients. Therefore, we work with experienced manufacturers who adhere to international quality standards.

Why Choose NINGBO INNO PHARMCHEM CO.,LTD. as Your Supplier?

Procuring chemical intermediates involves more than just finding the lowest price. It requires a partner who guarantees quality, reliable delivery, and expert technical support. At NINGBO INNO PHARMCHEM CO.,LTD., we offer:

  • High-Quality Products: Our 5-Bromoisophthalonitrile is sourced with a minimum purity of 97%, ensuring efficacy in your applications.
  • Competitive Pricing: As a direct manufacturer and supplier, we provide competitive prices, especially for bulk purchases. Request a quote to explore our pricing structures.
  • Technical Expertise: Our team possesses deep knowledge of chemical synthesis and applications, ready to assist with your inquiries.
  • Supply Chain Reliability: We ensure consistent availability and timely delivery, minimizing disruptions to your research and production schedules.

For procurement managers and R&D scientists, securing a dependable source for critical intermediates like 5-Bromoisophthalonitrile is a strategic advantage. By partnering with NINGBO INNO PHARMCHEM CO.,LTD., you gain access to premium chemical building blocks, competitive pricing, and a commitment to your success. Explore our offerings and request a sample or a quote today to elevate your chemical synthesis endeavors.