Mastering Peptide Synthesis: The Role of Boc-Tyr-OH
In the intricate world of peptide synthesis, precision and purity are paramount. For researchers and manufacturers alike, selecting the right building blocks can significantly impact the success of a project. One such indispensable compound is Boc-Tyr-OH, also known as N-Boc-L-tyrosine. This N-protected amino acid derivative is a cornerstone in solid-phase peptide synthesis (SPPS), particularly in the widely adopted Boc strategy. Understanding its properties and sourcing it from a reputable supplier is crucial for achieving optimal results.
Boc-Tyr-OH (CAS: 3978-80-1) features a tert-butyloxycarbonyl (Boc) group protecting the alpha-amino group of L-tyrosine. This protection is vital, as it prevents unwanted side reactions during the peptide chain elongation process. The Boc group is readily cleaved under mildly acidic conditions, typically using trifluoroacetic acid (TFA), regenerating the free amine for the next coupling step. Tyrosine, with its phenolic hydroxyl group, often requires additional protection during synthesis to prevent side reactions. However, Boc-Tyr-OH in its basic form is commonly used, with the understanding that the phenolic hydroxyl may undergo certain reactions or require specific coupling conditions depending on the peptide sequence and overall synthesis strategy.
The benefits of using Boc-Tyr-OH are manifold. Its stability and solubility in common organic solvents used in SPPS, such as dimethylformamide (DMF) and dichloromethane (DCM), make it easy to handle and incorporate into the synthesis resin. As a key intermediate, its availability from a reliable manufacturer in China ensures a steady supply for both laboratory-scale research and industrial production. For procurement managers and research scientists, identifying a trustworthy supplier that offers competitive Boc-Tyr-OH prices is a strategic advantage.
When considering where to buy Boc-Tyr-OH, several factors come into play: purity, consistency, and cost. A high-purity product guarantees efficient coupling and minimizes the risk of impurities in the final peptide. Consistent batch-to-batch quality is essential for reproducible scientific outcomes. Therefore, partnering with a manufacturer that adheres to strict quality control measures is imperative. We, as a dedicated supplier of amino acid derivatives and pharmaceutical intermediates, pride ourselves on delivering Boc-Tyr-OH that meets these exacting standards. Our commitment extends to providing exceptional value, making us a preferred choice for researchers and companies looking to purchase Boc-Tyr-OH.
In conclusion, Boc-Tyr-OH is more than just a chemical reagent; it is an enabler of scientific discovery in peptide-based therapeutics, diagnostics, and research. By understanding its role and ensuring a reliable source for high-quality Boc-Tyr-OH, you can confidently advance your projects. We invite you to inquire about our product availability and pricing for your next peptide synthesis endeavor.
Perspectives & Insights
Molecule Vision 7
“However, Boc-Tyr-OH in its basic form is commonly used, with the understanding that the phenolic hydroxyl may undergo certain reactions or require specific coupling conditions depending on the peptide sequence and overall synthesis strategy.”
Alpha Origin 24
“Its stability and solubility in common organic solvents used in SPPS, such as dimethylformamide (DMF) and dichloromethane (DCM), make it easy to handle and incorporate into the synthesis resin.”
Future Analyst X
“As a key intermediate, its availability from a reliable manufacturer in China ensures a steady supply for both laboratory-scale research and industrial production.”