In the realm of synthetic chemistry, few molecules offer the precise combination of protection, reactivity, and structural utility as Boc-Tyr-OH. Known chemically as N-Boc-L-tyrosine (CAS: 3978-80-1), this derivative of the amino acid tyrosine is a cornerstone reagent, particularly in the fields of peptide synthesis and pharmaceutical development. Its chemical versatility stems from the strategic placement of the tert-butyloxycarbonyl (Boc) protecting group on the alpha-amino nitrogen and the inherent functionality of the tyrosine side chain.

The defining feature of Boc-Tyr-OH is the Boc protecting group. This group is stable under a variety of reaction conditions, including basic and nucleophilic environments, making it ideal for protecting the amino terminus of amino acids during peptide chain elongation. Its facile removal under mildly acidic conditions, such as treatment with trifluoroacetic acid (TFA), cleanly regenerates the free amine, ready for the next coupling reaction. This selective deprotection is fundamental to the success of solid-phase peptide synthesis (SPPS) methodologies, including the widely used Boc strategy.

Beyond its role in peptide synthesis, Boc-Tyr-OH serves as a valuable chiral building block in broader organic synthesis. The tyrosine side chain, featuring a phenolic hydroxyl group, can be further modified or can participate in reactions that introduce complex structural motifs. This makes it an attractive starting material or intermediate for synthesizing bioactive molecules, drug candidates, and specialty chemicals. When researchers decide to buy Boc-Tyr-OH, they are securing a reagent that offers multiple synthetic avenues.

For chemists and researchers, understanding the solubility and handling characteristics of Boc-Tyr-OH is crucial. It typically presents as a white to off-white crystalline powder, soluble in organic solvents like methanol, ethanol, DMSO, and DMF, but sparingly soluble in water. Proper storage, often at cold temperatures (e.g., -20°C), is recommended to maintain its integrity. As a leading manufacturer and supplier, we ensure that the Boc-Tyr-OH we provide adheres to strict purity standards, which is vital for consistent reaction outcomes and high yields. Our aim is to be your trusted source for this versatile chemical intermediate.

In summary, the chemical versatility of Boc-Tyr-OH makes it an indispensable reagent for chemists. Its well-defined protective group chemistry and reactive side chain offer significant advantages in both peptide synthesis and the creation of complex organic molecules for pharmaceutical research. We invite you to partner with us to procure high-quality Boc-Tyr-OH, and experience the reliability and expertise of a dedicated chemical supplier.