In the dynamic world of chemical synthesis, the Suzuki-Miyaura coupling reaction stands as a cornerstone for creating carbon-carbon bonds. At the heart of many successful Suzuki coupling applications lies a reliable supply of high-quality organoboron reagents. Among these, 4-Butylphenylboronic Acid (CAS: 145240-28-4) has emerged as a particularly versatile and sought-after compound. For researchers and procurement managers in the pharmaceutical, agrochemical, and material science sectors, understanding its properties and sourcing effectively is paramount.

The Importance of 4-Butylphenylboronic Acid in Synthesis

4-Butylphenylboronic Acid is an organoboron compound characterized by its phenyl ring substituted with a butyl group at the para position and a boronic acid functional group. This specific structure imparts several key advantages. The presence of the butyl chain enhances its lipophilicity and solubility in a wide range of organic solvents, which is a critical factor for successful reaction kinetics in organic synthesis. This improved solubility often translates to better handling and more efficient reaction processing compared to less soluble analogues.

Its primary application is as a coupling partner in the Suzuki-Miyaura reaction. This palladium-catalyzed cross-coupling reaction is a powerful tool for constructing biaryl compounds, conjugated systems, and other complex organic molecules. The boronic acid moiety readily participates in the transmetalation step of the catalytic cycle, allowing for the efficient formation of new carbon-carbon bonds. This makes 4-Butylphenylboronic Acid an indispensable building block in the synthesis of pharmaceuticals, advanced materials, and natural products.

Sourcing Quality and Reliability: A Manufacturer's Perspective

For businesses looking to buy 4-Butylphenylboronic Acid, choosing a reputable manufacturer and supplier is crucial. The quality of the boronic acid, particularly its purity and consistency, directly impacts the yield and success rate of downstream synthetic processes. Impurities can lead to unwanted side reactions, reduced yields, and complex purification challenges. Therefore, opting for a supplier that guarantees high purity, such as 4-Butylphenylboronic Acid with ≥98% HPLC purity, is a wise investment.

As a trusted manufacturer, we understand the critical role that reliable chemical supply plays in your operations. We offer 4-Butylphenylboronic Acid with a commitment to quality assurance, ensuring that each batch meets stringent specifications. This dedication allows us to serve as a dependable supplier for companies worldwide, providing competitive pricing and timely delivery. Whether you require small quantities for R&D or bulk orders for manufacturing, our production capabilities are designed to meet diverse needs.

Applications Across Industries

The utility of 4-Butylphenylboronic Acid extends across multiple industries:

  • Pharmaceutical Development: It serves as a key intermediate in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs). Its ability to participate in C-C bond formation is vital for constructing complex molecular scaffolds found in many modern medicines. Researchers often seek reliable sources for pharmaceutical intermediates to streamline their drug discovery and development pipelines.
  • Material Science: In material science, this boronic acid derivative is employed in the synthesis of novel polymers, liquid crystals, and organic electronic materials. The incorporation of the butylphenyl group can modify the electronic and physical properties of the final materials, leading to innovations in areas like OLEDs and advanced composites.
  • Organic Synthesis: Beyond specific industries, 4-Butylphenylboronic Acid is a staple reagent for organic chemists engaged in custom synthesis projects, methodology development, and the total synthesis of natural products. Its predictable reactivity in Suzuki couplings makes it a go-to choice for many synthetic challenges.

Choosing the Right Partner for Your Chemical Needs

When you need to purchase 4-Butylphenylboronic Acid, consider a supplier that offers not only high-quality products but also comprehensive support. This includes providing detailed technical specifications, safety data sheets (SDS), and responsive customer service. Many suppliers also offer custom synthesis services, allowing for tailored production of specific grades or derivatives to meet unique project requirements. Partnering with a manufacturer that prioritizes innovation and customer satisfaction ensures that your chemical sourcing is efficient and effective.

In conclusion, 4-Butylphenylboronic Acid is more than just a chemical reagent; it's an enabler of progress in chemical synthesis. By understanding its advantages and securing a reliable supply from a quality-focused manufacturer, you can confidently drive your research and production forward.