Methyl 2,3-dichloropropionate (CAS 3674-09-7) is a chemical compound that serves as an essential intermediate in various industrial applications, most notably in the pharmaceutical and fine chemical sectors. Understanding its properties, synthesis, and the global supply chain is crucial for professionals seeking to procure this compound efficiently and economically. This article provides an in-depth look at Methyl 2,3-dichloropropionate for those looking to buy it for their research or manufacturing needs.

Understanding the Chemical Profile

Methyl 2,3-dichloropropionate is an organochlorine compound with the molecular formula C4H6Cl2O2. It is recognized for its appearance as a clear, colorless to slightly yellow liquid. Key physical properties include a density of 1.328 g/mL at room temperature and a boiling point of 92°C at 50 mmHg. Its flash point of 42°C highlights the need for appropriate handling and storage. The compound is typically supplied with a minimum purity of 97%, making it suitable for demanding synthetic processes where high purity is critical.

Synthesis and Manufacturing Processes

The production of Methyl 2,3-dichloropropionate commonly involves the direct chlorination of methyl acrylate. This process requires careful control of reaction conditions, such as temperature and the rate of chlorine addition, to optimize yield and purity. For instance, a reported synthesis involves reacting methyl acrylate with chlorine gas in the presence of DMF, followed by vacuum distillation to isolate the desired product. This controlled manufacturing process ensures that the resulting intermediate meets the high standards required for its applications. As a reliable manufacturer, understanding these production nuances is key to delivering quality.

Key Applications and Uses

The primary application domain for Methyl 2,3-dichloropropionate is its role as a pharmaceutical intermediate. It is frequently used as a building block in the multi-step synthesis of complex pharmaceutical compounds and active pharmaceutical ingredients (APIs). Beyond pharmaceuticals, it is also valued in general organic synthesis for introducing specific chemical functionalities. Its utility extends to research laboratories and chemical production facilities worldwide. Professionals seeking to integrate this compound into their processes will find it available from specialized chemical suppliers who focus on providing high-quality intermediates.

Navigating the Global Supply Chain

The global market for Methyl 2,3-dichloropropionate is robust, with many suppliers operating internationally. China is a major source for this chemical intermediate, hosting numerous manufacturers capable of producing it at scale. When selecting a supplier, it is essential to consider their reliability, product quality (especially purity), and competitive pricing. Researching the typical Methyl 2,3-dichloropropionate price and delivery times is a prudent step for any procurement manager. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are recognized for their commitment to providing high-quality chemical intermediates and robust supply chain solutions, making them a valuable partner for businesses globally.

Conclusion

Methyl 2,3-dichloropropionate is a compound of significant industrial importance, particularly in pharmaceutical synthesis. By understanding its chemical properties, synthesis methods, and the advantages of sourcing from reputable global suppliers, businesses can ensure efficient and cost-effective procurement. A commitment to quality and reliability from the manufacturer is key to leveraging this intermediate effectively.