In the intricate world of pharmaceutical manufacturing, the quality of raw materials and intermediates directly dictates the success of the final drug product. Methyl 5-formyl-2-methoxybenzoate (CAS 78515-16-9) stands out as a vital intermediate, particularly in the synthesis of Eluxadoline, a medication used to treat irritable bowel syndrome. This article delves into its chemical characteristics, applications, and the advantages of sourcing it from reliable manufacturers.

Chemical Profile and Specifications

Methyl 5-formyl-2-methoxybenzoate is an organic compound with the molecular formula C10H10O4 and a molecular weight of 194.184 g/mol. It is typically described as a white to off-white powder, with a melting point in the range of 86-87°C. Its chemical structure features a benzoate ester with formyl and methoxy substituents, making it a versatile building block in organic synthesis. Manufacturers often guarantee a purity of 97.0% or higher, which is critical for its use in pharmaceutical applications.

Primary Applications in Pharmaceutical Synthesis

The most prominent application of methyl 5-formyl-2-methoxybenzoate is its role as a key intermediate in the synthesis of Eluxadoline. Eluxadoline is a gastrointestinal drug that targets specific receptors in the gut to alleviate symptoms of IBS. The efficient synthesis of Eluxadoline relies heavily on the quality and availability of its precursors, making methyl 5-formyl-2-methoxybenzoate a sought-after compound for pharmaceutical companies.

Furthermore, this intermediate finds application in the development of other therapeutic agents. It is used in synthesizing compounds that act as peroxisome proliferator-activated receptor (PPAR) activators and as precursors for 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene derivatives, which are known PTP1B inhibitors. These applications highlight its importance in research and development for metabolic disorders and other health conditions.

Why Choose a Specialized Manufacturer?

When you need to buy methyl 5-formyl-2-methoxybenzoate, partnering with a specialized manufacturer offers distinct advantages. NINGBO INNO PHARMCHEM CO.,LTD., for example, has extensive experience in producing high-quality pharmaceutical intermediates. This ensures that you receive a product that meets stringent specifications, supporting your R&D efforts and manufacturing processes. Accessing a dependable supplier in China can also provide cost efficiencies without compromising on quality. They can offer competitive price options for this crucial intermediate, allowing your company to optimize production costs.

For researchers and manufacturers, understanding the properties and applications of key intermediates like methyl 5-formyl-2-methoxybenzoate is essential. By selecting a trusted manufacturer, you ensure the integrity of your drug synthesis and contribute to the development of effective therapeutic solutions.