While Methyl 5-formyl-2-methoxybenzoate (CAS 78515-16-9) is widely recognized as a crucial intermediate for the synthesis of Eluxadoline, its utility extends to other significant areas within pharmaceutical research and development. This versatile compound's chemical structure lends itself to various synthetic pathways, making it a valuable asset for scientists exploring novel therapeutic agents.

Eluxadoline Synthesis: The Primary Role

The most established application for Methyl 5-formyl-2-methoxybenzoate is in the production of Eluxadoline, a medication commonly prescribed for irritable bowel syndrome. As a direct precursor, the availability of this high-purity intermediate is critical for pharmaceutical companies manufacturing Eluxadoline. Ensuring a stable supply from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is key for maintaining production timelines and quality standards.

Exploring Wider Applications in Drug Discovery

Beyond Eluxadoline, Methyl 5-formyl-2-methoxybenzoate serves as a foundational intermediate in the synthesis of other promising drug candidates:

  • PPAR Activators: The compound is instrumental in creating peroxisome proliferator-activated receptor (PPAR) activators. PPARs are nuclear receptor proteins that regulate the expression of genes involved in energy homeostasis, inflammation, and cell differentiation. Drugs targeting PPARs are used in treating conditions such as type 2 diabetes, dyslipidemia, and obesity. Researchers looking to synthesize novel PPAR activators can reliably buy methyl 5-formyl-2-methoxybenzoate for their R&D projects.
  • PTP1B Inhibitors: Methyl 5-formyl-2-methoxybenzoate is also employed in the preparation of specific 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene derivatives. These derivatives function as protein tyrosine phosphatase 1B (PTP1B) inhibitors. PTP1B is a key negative regulator of insulin signaling and leptin signaling, making its inhibitors potential therapeutic agents for diabetes and obesity. Scientists involved in this research can source this intermediate from established chemical suppliers.

The Value Proposition for R&D Professionals

For research scientists and procurement managers, having a reliable source for such versatile intermediates is invaluable. A dependable supplier in China, such as NINGBO INNO PHARMCHEM CO.,LTD., can provide the necessary chemical with guaranteed purity, facilitating uninterrupted research and development cycles. Exploring the various applications of Methyl 5-formyl-2-methoxybenzoate allows drug discovery teams to leverage its potential for developing next-generation therapeutics.

Whether your focus is on established drugs like Eluxadoline or pioneering research into metabolic and inflammatory diseases, securing a consistent supply of high-quality Methyl 5-formyl-2-methoxybenzoate is a strategic advantage. We encourage you to inquire about this versatile intermediate to support your ongoing projects.