In the realm of chemical synthesis, amino acid derivatives play an indispensable role, acting as the fundamental building blocks for a vast array of complex molecules. Among these, Methyl L-Tyrosinate Hydrochloride (H-Tyr-OMe·HCl), identified by its CAS number 3417-91-2, is a compound of significant interest to researchers and manufacturers alike. This article provides a detailed look into its characteristics, applications, and the critical aspects of sourcing this valuable chemical.

Chemical Profile of Methyl L-Tyrosinate Hydrochloride

Methyl L-Tyrosinate Hydrochloride is essentially the methyl ester of the amino acid L-tyrosine, presented as its hydrochloride salt. It typically appears as a white to off-white crystalline powder, indicating a high degree of purity, often exceeding 98% as verified by High-Performance Liquid Chromatography (HPLC). Its molecular formula is C10H14ClNO3, with a molecular weight of 231.68 g/mol. The compound's physical properties, such as its melting point (around 192°C with decomposition) and solubility characteristics, are well-documented and crucial for its effective use in various chemical processes.

Key Applications Driving Demand

The demand for Methyl L-Tyrosinate Hydrochloride is primarily driven by its utility in two major sectors: peptide synthesis and pharmaceutical intermediate production. As a protected form of tyrosine's methyl ester, it is readily incorporated into peptide chains during both solid-phase and solution-phase synthesis. This makes it an essential component for creating peptides used in pharmaceuticals, cosmetics, and advanced biochemical research.

Furthermore, H-Tyr-OMe HCl serves as a versatile intermediate in the broader field of organic synthesis. Its reactive functional groups allow for further chemical modifications, making it a valuable starting material for developing new drugs, agrochemicals, and specialty materials. For any chemist looking to buy this compound, understanding these applications is key to appreciating its market value.

Sourcing Strategy: Purity, Price, and Reliability

When procuring Methyl L-Tyrosinate Hydrochloride, selecting a reliable supplier is paramount. As a B2B purchaser, focusing on manufacturers who can consistently deliver high-purity material (e.g., >98% HPLC) at competitive prices is essential. Many companies offer this compound, but vetting potential partners is crucial. Key considerations include:

  • Quality Assurance: Does the supplier provide a Certificate of Analysis (CoA) for each batch?
  • Manufacturing Capability: Is the supplier a direct manufacturer, or a distributor? Direct manufacturers often offer better pricing and more control over quality.
  • Customer Service: Does the supplier offer technical support and responsive communication?
  • Delivery Reliability: Can they meet your required delivery timelines, especially for bulk orders?

Conclusion

Methyl L-Tyrosinate Hydrochloride is a fundamental chemical building block with significant applications in peptide synthesis and pharmaceutical development. Its importance necessitates careful consideration of sourcing strategies, prioritizing purity, competitive pricing, and supplier reliability. By understanding its chemical properties and application scope, procurement professionals can make informed decisions to secure this vital amino acid derivative for their manufacturing and research needs.