In the realm of pharmaceutical manufacturing, the precision and quality of chemical intermediates are fundamental to the successful development and production of APIs. (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid, widely known as MOC-L-Valine and carrying the CAS number 74761-42-5, stands out as a critical building block. Its unique structure and protected functional group make it an indispensable component in sophisticated organic synthesis, particularly for antiviral drugs.

The compound's synthesis typically involves protecting the amino group of L-valine with a methoxycarbonyl group. This process, often carried out using methyl chloroformate under controlled conditions, yields a stable intermediate suitable for further chemical transformations. The resulting MOC-L-Valine is a chiral molecule with a defined stereochemistry, a critical factor for its biological activity when incorporated into drug molecules. Its physical form as a white to off-white powder, with a specified melting point range, aids in its handling and processing by pharmaceutical manufacturers.

The significance of MOC-L-Valine in the pharmaceutical industry is most notably demonstrated by its application in the synthesis of Ledipasvir and Daclatasvir. These drugs are highly effective treatments for Hepatitis C, a significant global health challenge. The precise incorporation of the valine moiety, delivered via MOC-L-Valine, is crucial for the efficacy and pharmacological profile of these antiviral agents. Consequently, the demand for high-purity MOC-L-Valine from reliable manufacturers is consistently strong.

For procurement specialists and research scientists, identifying a dependable supplier for CAS 74761-42-5 is paramount. Factors such as consistent batch-to-batch quality, high assay purity (≥99.0%), and robust supply chain management are essential. Working with manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., who specialize in pharmaceutical intermediates and have a proven track record, ensures that you receive materials that meet stringent industry standards. This reliability minimizes risks in R&D projects and streamlines production processes.

Moreover, as the pharmaceutical landscape evolves, the need for specialized chiral building blocks like MOC-L-Valine will continue to grow. Its versatility in peptide synthesis and the development of other therapeutic classes further solidifies its importance. By understanding its chemical attributes and application relevance, pharmaceutical companies can make informed decisions when sourcing this vital intermediate, ultimately contributing to the delivery of safe and effective medicines to patients worldwide.