For professionals in the pharmaceutical and biochemical sectors, sourcing high-quality N-alpha-Fmoc-L-Aspartic Acid Alpha-Allyl Ester (also known as Fmoc-Asp-OAll, CAS 144120-53-6) is fundamental to successful peptide synthesis. This critical building block, with its unique protective group strategy, enables the construction of intricate peptide sequences. This guide aims to equip procurement managers and research scientists with the knowledge to effectively buy this essential intermediate, highlighting the advantages of partnering with experienced Chinese manufacturers and suppliers.

The value of Fmoc-Asp-OAll in solid-phase peptide synthesis, particularly within the Fmoc strategy, cannot be overstated. The molecule features an Fmoc group safeguarding the alpha-amino terminus, a standard in this method. More significantly, the allyl ester attached to the beta-carboxyl group of the aspartic acid side chain provides an orthogonal protecting group. This allows for selective removal of the allyl ester using mild palladium catalysts, a method that is compatible with other protecting groups that might be sensitive to stronger acidic or basic conditions. This selective deprotection capability is crucial for introducing specific modifications or for constructing peptides with unusual side-chain functionalities. As a white powder, it offers good stability when stored at 2-8°C, ensuring its efficacy for synthesis.

When you are ready to buy N-alpha-Fmoc-L-Aspartic Acid Alpha-Allyl Ester, prioritizing purity and reliability is paramount. A standard purity of ≥98.0% (by HPLC) is typically expected for demanding applications in drug discovery and research. Chinese manufacturers have become global leaders in producing specialty chemicals like Fmoc-Asp-OAll, often providing a compelling combination of quality, competitive pricing, and scalable production. Identifying a reputable supplier involves due diligence, including checking for product specifications, quality certifications, and customer service responsiveness. We are committed to being that reliable source for your procurement needs.

The demand for advanced peptide synthesis reagents is driven by ongoing innovations in therapeutics, diagnostics, and biochemical research. Fmoc-Asp-OAll is frequently sought after by researchers developing novel peptide-based drugs or probing biological pathways. We understand the importance of a consistent and dependable supply chain. Our manufacturing processes are geared towards ensuring high purity and availability, whether you need small research quantities or larger commercial batches. We invite you to contact us for detailed product inquiries and to obtain a quote for buying Fmoc-Asp-OAll.

In conclusion, N-alpha-Fmoc-L-Aspartic Acid Alpha-Allyl Ester (Fmoc-Asp-OAll, CAS 144120-53-6) is a critical intermediate for advanced peptide synthesis, offering a vital orthogonal protection strategy. We encourage you to partner with us, a leading Chinese manufacturer and supplier, to ensure you buy a high-quality product that meets your stringent research and development requirements.