Navigating Daclizumab: A Supplier's Guide to Research Applications
As a leading supplier of specialized biochemicals, we understand the critical role that compounds like Daclizumab play in advancing scientific research. Daclizumab, a humanized monoclonal antibody targeting the IL-2 receptor alpha subunit (CD25), possesses a unique profile that continues to be of interest to researchers despite its clinical withdrawal. This article provides an overview for R&D scientists and procurement managers looking to buy Daclizumab for their laboratory needs.
Daclizumab's mechanism of action involves reversibly binding to CD25, thereby inhibiting the interleukin-2 (IL-2) pathway. This targeted immunosuppression was the basis for its use in preventing organ transplant rejection and, more recently, in treating relapsing forms of multiple sclerosis. While these clinical applications have ceased due to safety concerns, the fundamental biological activity of Daclizumab makes it an invaluable research tool. For laboratories investigating immune system regulation, autoimmune diseases, or the development of novel antibody therapies, understanding how to source and utilize Daclizumab is key.
When procuring Daclizumab, several factors are paramount for B2B customers. Firstly, product purity and quality are non-negotiable. Reputable manufacturers and suppliers ensure that their Daclizumab meets stringent specifications, often verified by Certificates of Analysis (CoA). This is especially important for research applications where lot-to-lot consistency is critical for reliable experimental outcomes. Secondly, understanding the supplier's logistical capabilities, such as cold chain management during shipping, is vital for preserving the integrity of this biological product.
The safety concerns that led to Daclizumab’s market withdrawal – including potential inflammatory brain disorders and liver toxicity – highlight the importance of handling and experimental design. Researchers utilizing Daclizumab should be fully aware of these potential risks and incorporate appropriate safety protocols. This awareness also informs the development of new therapies, as lessons learned from Daclizumab’s adverse events can guide the design of safer, more selective immunomodulatory agents. Therefore, purchasing Daclizumab for comparative studies or mechanism of action research is a common practice.
For procurement managers, identifying reliable manufacturers and distributors is crucial. Many suppliers worldwide, including those in China, offer Daclizumab. When comparing options, consider factors such as pricing, availability, technical support, and the supplier's reputation within the scientific community. A thorough due diligence process will help ensure you are purchasing a high-quality product that meets your research objectives. Engaging with a trusted chemical supplier for your Daclizumab needs provides the assurance necessary for successful research outcomes.
In summary, Daclizumab, despite its clinical discontinuation, remains a scientifically significant compound. Its utility in immunological research, particularly in understanding T-cell mediated responses and autoimmune pathways, continues to drive demand. By partnering with knowledgeable suppliers and prioritizing product quality and safety information, research institutions can effectively leverage Daclizumab to advance their scientific investigations.
Perspectives & Insights
Data Seeker X
“For laboratories investigating immune system regulation, autoimmune diseases, or the development of novel antibody therapies, understanding how to source and utilize Daclizumab is key.”
Chem Reader AI
“Reputable manufacturers and suppliers ensure that their Daclizumab meets stringent specifications, often verified by Certificates of Analysis (CoA).”
Agile Vision 2025
“This is especially important for research applications where lot-to-lot consistency is critical for reliable experimental outcomes.”