For professionals involved in pharmaceutical synthesis, particularly the production of Aripiprazole, understanding the market dynamics of key intermediates like 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone (CAS: 22246-18-0) is crucial. The interplay between purity, price, and supplier reliability dictates the success of procurement efforts. This guide aims to help buyers navigate these aspects effectively.

Purity is paramount when sourcing pharmaceutical intermediates. 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone typically needs to meet stringent purity standards, often specified as an assay of ≥98.0%. This high level of purity ensures minimal unwanted byproducts in the subsequent synthesis steps, which is vital for the efficacy and safety of the final API, Aripiprazole. When requesting product information, always verify the stated purity levels and look for detailed Certificates of Analysis (CoA) from suppliers. The appearance, usually an off-white powder, is also a visual indicator, though analytical data provides definitive quality assurance.

The price of 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone can vary based on several factors, including order quantity, supplier origin, and market demand. As a primary intermediate for Aripiprazole, its pricing is closely tied to the pharmaceutical market's dynamics. For buyers, conducting thorough market research and obtaining multiple quotes is essential. Using search terms such as '7-Hydroxy-3,4-dihydro-2(1H)-quinolinone price' or 'buy 22246-18-0' will provide a basis for comparison.

Manufacturers, particularly those in China, often offer the most competitive pricing, especially for bulk orders. When requesting quotes, clearly specify the required quantity, purity, and any specific packaging or delivery requirements. This detailed approach helps suppliers provide accurate quotations. Furthermore, inquire about the supplier’s production capacity and lead times to ensure they can meet your ongoing supply needs.

Beyond its established use, the compound’s potential as an antitumor agent adds another layer of interest. This broader application might influence demand and pricing in research contexts. Therefore, whether for large-scale API production or specialized research, a strategic approach to sourcing is necessary.

In essence, procuring 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone requires a careful balance between achieving high purity and securing a cost-effective price. By diligently researching suppliers, verifying product specifications, and engaging in informed price negotiations, procurement specialists can ensure a reliable and high-quality supply of this critical pharmaceutical intermediate. Partnering with experienced manufacturers and suppliers in China offers a strong avenue for achieving these objectives.