In the dynamic field of pharmaceutical development, the precise selection of chemical components is critical for creating effective and stable formulations. 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (O-LysoPE), a well-characterized lysophospholipid, is increasingly recognized for its potential as a pharmaceutical intermediate and excipient. For drug developers and formulation scientists seeking to enhance drug delivery and efficacy, understanding the properties and sourcing of O-LysoPE from a reliable manufacturer is a strategic advantage.

O-LysoPE: A Versatile Pharmaceutical Intermediate

O-LysoPE, identified by its CAS number 89576-29-4, is a naturally occurring lipid that plays diverse roles in biological systems. Its amphipathic nature, with a hydrophilic head group and a hydrophobic tail, makes it an excellent candidate for incorporation into liposomal structures, micelles, and other nanocarriers used in advanced drug delivery systems. As a high-purity compound, typically sourced with >98% purity, O-LysoPE can contribute to the stability and biocompatibility of these formulations. When you buy O-LysoPE, you are acquiring a molecule with potential to improve drug solubility, bioavailability, and targeted delivery.

Applications in Drug Delivery Systems

The utility of O-LysoPE in pharmaceutical applications is multifaceted:

  • Liposome Formation: Lysophospholipids like O-LysoPE can influence the fluidity and stability of liposomal membranes. Their incorporation can be optimized to control drug release profiles and enhance the interaction of liposomes with biological tissues.
  • Enhancing Drug Solubility: For poorly water-soluble active pharmaceutical ingredients (APIs), O-LysoPE can act as a solubilizing agent, forming mixed micelles that improve the aqueous solubility and subsequent delivery of the drug.
  • Bioavailability Enhancement: By aiding in drug absorption and protecting the API from degradation, O-LysoPE can contribute to improved overall bioavailability, leading to more effective therapeutic outcomes.
  • Research and Development: As a building block for more complex lipid structures, O-LysoPE is invaluable in R&D for creating novel lipid-based therapeutic agents and delivery vehicles. Investigating the price and availability from a reputable chemical supplier in China is a key step for cost-effective development.

Choosing a Reliable Supplier for Pharmaceutical Needs

When sourcing O-LysoPE for pharmaceutical applications, stringent quality standards must be met. A dependable manufacturer will provide:

  • Guaranteed High Purity: Essential for pharmaceutical applications where even trace impurities can impact safety and efficacy.
  • Comprehensive Documentation: Including Certificates of Analysis and relevant safety data sheets to meet regulatory requirements.
  • Consistent Supply: Ensuring that production can scale with demand and that your supply chain remains robust.
  • Technical Support: Expert advice on handling, storage, and formulation considerations.

For companies looking to purchase O-LysoPE, identifying a trusted manufacturer in China can provide access to high-quality biochemicals at competitive prices. Investing in a premium O-LysoPE product from a reliable supplier is a critical step towards successful pharmaceutical development.