Optimized Synthesis of Lifitegrast Key Intermediate: Benzofuran-6-Carboxylic Acid
The quest for more efficient and cost-effective pharmaceutical manufacturing processes drives continuous innovation in synthetic chemistry. For the production of Lifitegrast, a significant therapeutic agent for dry eye disease, Benzofuran-6-carboxylic Acid (CAS: 77095-51-3) serves as a fundamental intermediate. NINGBO INNO PHARMCHEM CO.,LTD., a dedicated manufacturer and supplier, specializes in optimizing the synthesis of such critical compounds, ensuring high purity and consistent availability for our global clientele.
Our research and development efforts have focused on enhancing the production of Benzofuran-6-carboxylic Acid. By refining the synthetic pathway, we have achieved a notable increase in yield and a reduction in production complexity. Starting from accessible precursors like 4-bromo-2-hydroxybenzaldehyde, our improved methodology delivers Benzofuran-6-carboxylic Acid with significantly higher efficiency compared to older, more challenging routes. This makes it more feasible for businesses to buy this chemical intermediate for their pharmaceutical projects.
Moreover, the overall process for Lifitegrast synthesis has seen advancements, including the optimization of hydrolysis steps, which are crucial for achieving the required purity of the final drug substance. The development of a process yielding Lifitegrast with >99.9% purity and an overall yield of 79% demonstrates our commitment to excellence. These advancements are vital for any R&D scientist or procurement manager seeking a reliable supplier for their active pharmaceutical ingredient needs. Sourcing this intermediate from a reputable manufacturer in China, such as NINGBO INNO PHARMCHEM CO.,LTD., guarantees adherence to strict quality standards.
For companies involved in the development and manufacturing of ophthalmic solutions or other pharmaceuticals requiring this specific intermediate, partnering with a knowledgeable supplier is key. We offer competitive pricing for Benzofuran-6-carboxylic Acid and are equipped to handle bulk orders, ensuring a stable supply for your production lines. If you are seeking a dependable source for this essential Lifitegrast intermediate, we encourage you to inquire about our product specifications and obtain a quote. Our team is ready to support your chemical sourcing needs.
Perspectives & Insights
Chem Catalyst Pro
“These advancements are vital for any R&D scientist or procurement manager seeking a reliable supplier for their active pharmaceutical ingredient needs.”
Agile Thinker 7
“Sourcing this intermediate from a reputable manufacturer in China, such as NINGBO INNO PHARMCHEM CO.”
Logic Spark 24
“For companies involved in the development and manufacturing of ophthalmic solutions or other pharmaceuticals requiring this specific intermediate, partnering with a knowledgeable supplier is key.”