The efficient and cost-effective synthesis of Active Pharmaceutical Ingredients (APIs) is at the core of pharmaceutical manufacturing. For antifungal drugs, specific chemical intermediates are vital, and one such compound is 1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole (CAS: 67085-12-5). This molecule serves as a critical building block in the production of butoconazole, an important antifungal medication. Understanding its properties and how to source it effectively is key for any manufacturer aiming for optimized production.

The Importance of Purity and Specification

1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole, with a molecular formula of C13H14Cl2N2, is typically supplied as a white powder. For pharmaceutical synthesis, high purity is non-negotiable. Manufacturers often guarantee an assay of u226598.0%, which is crucial for achieving high yields and minimizing the formation of unwanted byproducts in the subsequent synthesis steps. The precise chemical structure and consistent purity of this intermediate directly impact the quality, efficacy, and safety of the final antifungal API.

When procurement managers are tasked with buying this compound, they must prioritize suppliers who can consistently deliver material that meets these stringent specifications. This often involves thorough due diligence on the manufacturer's quality management systems, production capabilities, and analytical testing protocols. Obtaining a Certificate of Analysis (CoA) for each batch is essential to verify that the material conforms to the required standards.

Strategic Sourcing for Production Efficiency

For companies looking to buy 1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole, strategic sourcing can lead to significant benefits in terms of cost and production efficiency. Identifying suppliers, particularly those in China known for their chemical manufacturing expertise, can provide access to competitive pricing and reliable supply chains. When evaluating potential suppliers, consider factors such as:

  • Manufacturing Capacity: Can the supplier meet your volume requirements for both pilot-scale and commercial production?
  • Quality Assurance: Does the supplier have robust quality control measures and provide comprehensive documentation (CoA, MSDS)?
  • Technical Support: Can the supplier offer technical assistance regarding product handling, storage, and application?
  • Regulatory Compliance: Does the supplier adhere to relevant industry regulations?

Engaging with a supplier early in the development process can also be advantageous. They can often provide valuable insights into the material's properties and assist in optimizing synthesis routes. For companies focused on research and development, smaller quantities of this intermediate can be procured to explore new formulations or alternative synthetic pathways.

Building Reliable Partnerships

Ultimately, securing a consistent and high-quality supply of 1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole is about building a reliable partnership with your chemical supplier. By prioritizing purity, engaging in thorough due diligence, and focusing on suppliers who offer competitive pricing and robust technical support, you can ensure the efficiency and success of your antifungal API manufacturing operations. Investigate your options to buy this critical intermediate and enhance your production capabilities.