For procurement specialists in the pharmaceutical industry, securing a consistent supply of high-quality intermediates is fundamental to successful drug manufacturing. 1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole (CAS: 67085-12-5) is one such compound, critically important as a precursor in the synthesis of the antifungal agent butoconazole. This article serves as a practical guide for procurement managers looking to source this vital chemical efficiently and effectively.

Understanding the Material: Key Specifications

The compound, with the molecular formula C13H14Cl2N2, is typically supplied as a white powder. Its primary value in pharmaceutical synthesis stems from its high purity, commonly specified at u226598.0% assay. This purity level is essential for ensuring the desired reaction outcomes, minimizing side reactions, and ultimately achieving the required quality for the final butoconazole API. Procurement managers must always verify these specifications with potential suppliers.

Beyond its primary use as a synthetic intermediate, this chemical is also recognized as a potential impurity in butoconazole formulations. Therefore, having access to well-characterized batches of this compound is also crucial for pharmaceutical companies establishing robust quality control protocols. When you decide to buy, ensuring the supplier can provide accurate Certificates of Analysis (CoAs) is a standard but critical step.

Selecting a Reliable Supplier: What to Look For

When sourcing chemical intermediates, especially for pharmaceutical applications, supplier reliability is paramount. Procurement managers should consider the following criteria when selecting a manufacturer or supplier for 1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole:

  • Quality Management Systems: Does the supplier operate under recognized quality standards (e.g., ISO, GMP)?
  • Manufacturing Capabilities: Can they meet current and future volume demands?
  • Technical Documentation: Do they consistently provide accurate CoAs, MSDS, and other relevant technical data?
  • Supply Chain Stability: What is their track record for on-time delivery and consistent product availability?
  • Pricing and Value: While purity is key, competitive pricing from manufacturers, especially those in established chemical hubs like China, can offer significant advantages.

Building a strong relationship with a trusted supplier can streamline the procurement process and mitigate risks associated with supply chain disruptions or quality issues. It is often beneficial to engage with suppliers early in the product development lifecycle.

Cost-Effective Purchasing Strategies

To optimize purchasing, procurement managers can explore several strategies. Firstly, consolidating orders with a single, reliable manufacturer can often lead to volume discounts and reduced logistical costs. Secondly, exploring long-term supply agreements can ensure price stability and guaranteed availability. Thirdly, staying informed about market trends and potential price fluctuations for chemical intermediates will enable more strategic purchasing decisions.

For pharmaceutical manufacturers, the decision to buy 1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole is a critical one that impacts product quality and production efficiency. By focusing on purity, supplier reliability, and strategic sourcing, procurement teams can secure this vital intermediate, paving the way for successful and compliant antifungal drug manufacturing.

Investigate your options for purchasing this essential pharmaceutical intermediate and build a partnership that supports your production goals.