For pharmaceutical manufacturers and R&D scientists focused on oncology therapeutics, securing a reliable supply of high-purity intermediates is paramount. One such critical component is 2,4-Dichloro-5-methoxyaniline (CAS: 98446-49-2), a key precursor in the synthesis of Bosutinib. This article delves into the importance of this compound and how to effectively source it from reputable manufacturers and suppliers, particularly those based in China.

Bosutinib is a potent tyrosine kinase inhibitor used in the treatment of chronic myelogenous leukemia (CML). Its complex synthesis pathway necessitates the use of precisely characterized building blocks. 2,4-Dichloro-5-methoxyaniline, with its specific chemical structure (Molecular Formula: C7H7Cl2NO), plays an indispensable role in constructing the Bosutinib molecule. The purity of this intermediate directly impacts the efficiency of the synthesis and the final drug product's quality.

When looking to buy 2,4-Dichloro-5-methoxyaniline, pharmaceutical professionals must prioritize suppliers who can guarantee a minimum purity of 98.0% (GC), as is standard for this product. Manufacturers in China have established themselves as significant global suppliers of fine chemicals and pharmaceutical intermediates, offering competitive pricing and large-scale production capabilities. Identifying a trustworthy manufacturer in China for this specific compound is key to ensuring a stable and cost-effective supply chain.

The CAS 98446-49-2 price can vary based on purity, quantity, and the supplier's service offerings. For bulk purchases, direct engagement with manufacturers or their authorized distributors can yield the best pricing. It is advisable to request quotations and sample batches to verify quality and consistency before committing to large orders. A reliable Bosutinib intermediate supplier will also provide comprehensive documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS).

Furthermore, understanding the product's physical characteristics is important. 2,4-Dichloro-5-methoxyaniline typically appears as a pale yellow solid with a melting point around 51°C. Its chemical properties, including solubility in solvents like chloroform and methanol, are also crucial considerations for process chemists. Ensuring that your pharmaceutical intermediate for sale meets these specifications is vital for successful downstream applications.

For companies seeking to optimize their Bosutinib production, partnering with a well-established 2,4-Dichloro-5-methoxyaniline supplier in China offers a strategic advantage. They can provide not only the required purity and quantity but also the technical support and regulatory understanding necessary for pharmaceutical manufacturing. By focusing on quality, reliability, and cost-effectiveness, procurement managers can secure this essential intermediate and contribute to the successful development and production of life-saving medications.