In the realm of organic synthesis, the strategic use of well-defined chemical intermediates is the cornerstone of efficient and successful reactions. 2-Fluoro-3-iodo-6-methylpyridine, bearing CAS number 884494-48-8, represents such a valuable intermediate. As a leading manufacturer and supplier of fine chemicals, our expertise lies in providing researchers and industrial chemists with high-quality building blocks that accelerate innovation. This article delves into the significance of 2-Fluoro-3-iodo-6-methylpyridine in chemical synthesis and offers practical insights from a manufacturer's perspective on its procurement and utilization.

The Chemical Profile of 2-Fluoro-3-iodo-6-methylpyridine

The molecular structure of 2-Fluoro-3-iodo-6-methylpyridine (C6H5FIN) is key to its utility. The presence of a fluorine atom, an iodine atom, and a methyl group on the pyridine ring creates a highly functionalized molecule. These functional groups offer distinct reactivity patterns: the iodine atom is an excellent leaving group for various cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig couplings), allowing for the introduction of diverse substituents. The fluorine atom can influence the electronic properties of the molecule and subsequent derivatives, often enhancing metabolic stability or modifying lipophilicity in drug candidates. The methyl group provides a point for further modification or steric influence. Typically supplied as a white powder with a purity of 98%, its physical properties, such as a boiling point of 233.1 °C, are critical for reaction design.

Manufacturer's Perspective: Ensuring Quality and Availability

As a dedicated manufacturer in China, our mission is to supply 2-Fluoro-3-iodo-6-methylpyridine that meets the stringent demands of modern chemical synthesis. Our production process is meticulously controlled to ensure consistent purity and the absence of critical impurities that could interfere with sensitive reactions. We understand that for chemists, reliability in supply is as important as product quality. Therefore, we maintain substantial production capacity and efficient logistics to meet varying order sizes, from gram-scale quantities for R&D laboratories to bulk orders for industrial applications.

Key aspects we focus on include:

  • Purity Standards: We consistently aim for 98% purity for 2-Fluoro-3-iodo-6-methylpyridine, backed by comprehensive analytical data.
  • Scalability: Our facilities are equipped to scale production, ensuring we can support your project from early-stage research through to commercial manufacturing.
  • Technical Data: Providing detailed technical documentation, including molecular structure, CAS number (884494-48-8), molecular weight, appearance, and safety data sheets (MSDS), is standard practice.
  • Logistics and Export: We have robust export capabilities, managing transportation via air, land, and sea, ensuring timely delivery to global destinations from our China-based facility.

Strategies for Efficient Procurement and Synthesis Planning

To optimize your chemical synthesis using 2-Fluoro-3-iodo-6-methylpyridine, consider these procurement strategies:

  • Early Engagement with Suppliers: Contacting manufacturers early in your project lifecycle allows for better planning and potential customization of specifications if needed.
  • Bulk Order Advantages: For larger synthesis campaigns, purchasing in bulk from a direct manufacturer like us can significantly reduce the overall cost per unit. This includes exploring various payment options (T/T, L/C) and incoterms.
  • Sample Testing: Always request samples to validate performance in your specific reaction conditions before placing a large order. This is crucial for any chemical intermediate purchase.
  • Understanding Reactivity: Familiarize yourself with common reactions involving halogenated pyridines, such as palladium-catalyzed cross-couplings, to maximize the synthetic utility of this versatile compound.

Conclusion

2-Fluoro-3-iodo-6-methylpyridine (CAS 884494-48-8) is a powerful tool for synthetic chemists. As a leading manufacturer and supplier, we are committed to providing the high-quality material and reliable service needed to drive your chemical synthesis projects forward. By partnering with an experienced producer, you can ensure access to this vital intermediate, optimize your reaction pathways, and ultimately bring your innovations to fruition more efficiently. We invite you to inquire about our manufacturing capabilities and obtain a quote for your next purchase of this essential fine chemical.