In the intricate field of peptide synthesis, the quality of raw materials directly impacts the success of research and development endeavors. For professionals in pharmaceutical R&D, contract research organizations (CROs), and academic institutions, securing reliable sources for critical reagents is paramount. Among these, Fmoc-4-carboxymethyl-piperazine stands out as a valuable building block, particularly for its role in solid-phase peptide synthesis (SPPS) and drug development.

Fmoc-4-carboxymethyl-piperazine, identified by its CAS number 180576-05-0, is a modified amino acid derivative that incorporates the Fmoc (fluorenylmethoxycarbonyl) protecting group. This group is indispensable in SPPS, allowing for selective deprotection and coupling steps without interfering with other parts of the growing peptide chain. The presence of the carboxymethyl moiety further enhances its utility, offering additional functionalization possibilities for drug design and bioconjugation applications.

Researchers often seek out suppliers who can guarantee high purity, typically above 98% as verified by HPLC. This level of purity is critical for ensuring efficient coupling reactions, minimizing side products, and ultimately achieving high yields of the target peptide. When you consider purchasing Fmoc-4-carboxymethyl-piperazine, looking for manufacturers who can provide comprehensive Certificates of Analysis (CoA) is a best practice. This documentation assures the quality and consistency of the material.

The applications of Fmoc-4-carboxymethyl-piperazine extend beyond basic peptide chain elongation. Its structure makes it an excellent candidate for creating complex peptide constructs, peptide-drug conjugates (PDCs), and for use in developing novel drug delivery systems. For procurement managers and research scientists, identifying a stable manufacturer in regions like China can offer significant advantages in terms of cost-effectiveness and supply chain reliability. Understanding the current price of Fmoc-4-carboxymethyl-piperazine can also aid in budgeting for large-scale synthesis projects.

To successfully integrate this compound into your workflow, consider the following:

  • Purity: Always prioritize products with demonstrated purity levels of 98% or higher.
  • Supplier Reputation: Partner with manufacturers and suppliers known for quality control and consistent product availability.
  • Technical Support: Engage with suppliers who can offer technical data and support for their products.
  • Pricing and Bulk Orders: For ongoing projects, explore bulk purchase options to optimize costs.

By focusing on these aspects, you can ensure that your procurement of Fmoc-4-carboxymethyl-piperazine supports your research goals effectively, leading to more robust and reproducible results in peptide synthesis and pharmaceutical development. As a dedicated supplier, we are here to meet your needs for this vital chemical intermediate.